Chandran Ramakrishna
Overview
Explore the profile of Chandran Ramakrishna including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1089
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Recent Articles
1.
Ramakrishna C, Mendonca S, Ruegger P, Kim J, Borneman J, Cantin E
PLoS One
. 2020 Aug;
15(8):e0237189.
PMID: 32760124
Herpes simplex virus 1 (HSV) is a ubiquitous human virus resident in a majority of the global population as a latent infection. Acyclovir (ACV), is the standard of care drug...
2.
Ramakrishna C, Corleto J, Ruegger P, Logan G, Peacock B, Mendonca S, et al.
Sci Rep
. 2020 Jan;
9(1):20324.
PMID: 31889131
Chemotherapy induced peripheral neuropathy (CIPN), a toxic side effect of some cancer treatments, negatively impacts patient outcomes and drastically reduces survivor's quality of life (QOL). Uncovering the mechanisms driving chemotherapy-induced...
3.
Ramakrishna C, Kujawski M, Chu H, Li L, Mazmanian S, Cantin E
Nat Commun
. 2019 May;
10(1):2153.
PMID: 31089128
The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prevent various peripheral and CNS sterile inflammatory disorders. Fatal herpes simplex encephalitis (HSE) results from immune pathology caused...
4.
Srikanth S, Woo J, Wu B, El-Sherbiny Y, Leung J, Chupradit K, et al.
Nat Immunol
. 2019 Jan;
20(2):152-162.
PMID: 30643259
Stimulator of interferon genes (STING) is an endoplasmic reticulum (ER) signaling adaptor that is essential for the type I interferon response to DNA pathogens. Aberrant activation of STING is linked...
5.
Ramakrishna C, Golub M, Chiang A, Hong T, Kalkum M, Cantin E
Behav Neurol
. 2018 Jan;
2017:5238402.
PMID: 29358844
Herpes simplex virus 1 (HSV) encephalitis (HSE) has serious neurological complications, involving behavioral and cognitive impairments that cause significant morbidity and a reduced quality of life. We showed that HSE...
6.
Ramakrishna C, Cantin E
PLoS Pathog
. 2018 Jan;
14(1):e1006822.
PMID: 29352287
Emergency hematopoiesis facilitates the rapid expansion of inflammatory immune cells in response to infections by pathogens, a process that must be carefully regulated to prevent potentially life threatening inflammatory responses....
7.
Kramer N, Wang W, Reyes E, Kumar B, Chen C, Ramakrishna C, et al.
Blood
. 2015 May;
125(24):3720-30.
PMID: 25931583
MicroRNAs (miRNAs) are a class of powerful posttranscriptional regulators implicated in the control of diverse biological processes, including regulation of hematopoiesis and the immune response. To define the biological functions...
8.
Ramakrishna C, Ferraioli A, Calle A, Nguyen T, Openshaw H, Lundberg P, et al.
PLoS Pathog
. 2015 Mar;
11(3):e1004730.
PMID: 25760441
The establishment of latent infections in sensory neurons is a remarkably effective immune evasion strategy that accounts for the widespread dissemination of life long Herpes Simplex Virus type 1 (HSV1)...
9.
Srivastava R, Ramakrishna C, Cantin E
J Gen Virol
. 2015 Feb;
96(Pt 6):1347-1357.
PMID: 25667322
West Nile virus (WNV), an important global human pathogen, targets neurons to cause lethal encephalitis, primarily in elderly and immunocompromised patients. Currently, there are no approved therapeutic agents or vaccines...
10.
Ramakrishna C, Cantin E
J Allergy Clin Immunol
. 2014 Dec;
134(6):1469.
PMID: 25441301
No abstract available.