Chandra Sekhar Reddy Chilamakuri
Overview
Explore the profile of Chandra Sekhar Reddy Chilamakuri including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
618
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0
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Recent Articles
1.
Skoufou-Papoutsaki N, Adler S, Mehmed S, Tume C, Olpe C, Morrissey E, et al.
EMBO Rep
. 2025 Feb;
26(5):1269-1289.
PMID: 39920335
Cancer driver mutations are defined by their high prevalence in cancers and presumed rarity in normal tissues. However, recent studies show that positive selection in normal epithelia can increase the...
2.
Kupp R, Ruff L, Terranova S, Nathan E, Ballereau S, Stark R, et al.
Cancer Discov
. 2021 Mar;
11(9):2216-2229.
PMID: 33741711
()-a gene of unknown function-partners with a variety of transcriptional coactivators in translocations that drive supratentorial ependymoma, a frequently lethal brain tumor. Understanding the function of is key to developing...
3.
Shu S, Wu H, Ge J, Zeid R, Harris I, Jovanovic B, et al.
Mol Cell
. 2020 May;
78(6):1096-1113.e8.
PMID: 32416067
BET bromodomain inhibitors (BBDIs) are candidate therapeutic agents for triple-negative breast cancer (TNBC) and other cancer types, but inherent and acquired resistance to BBDIs limits their potential clinical use. Using...
4.
Nagarajan S, Rao S, Sutton J, Cheeseman D, Dunn S, Papachristou E, et al.
Nat Genet
. 2020 Feb;
52(3):354.
PMID: 32005967
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Nagarajan S, Rao S, Sutton J, Cheeseman D, Dunn S, Papachristou E, et al.
Nat Genet
. 2020 Jan;
52(2):187-197.
PMID: 31913353
Using genome-wide clustered regularly interspaced short palindromic repeats (CRISPR) screens to understand endocrine drug resistance, we discovered ARID1A and other SWI/SNF complex components as the factors most critically required for...
6.
Cidado J, Boiko S, Proia T, Ferguson D, Criscione S, San Martin M, et al.
Clin Cancer Res
. 2019 Nov;
26(4):922-934.
PMID: 31699827
Purpose: Cyclin-dependent kinase 9 (CDK9) is a transcriptional regulator and potential therapeutic target for many cancers. Multiple nonselective CDK9 inhibitors have progressed clinically but were limited by a narrow therapeutic...
7.
Peluffo G, Subedee A, Harper N, Kingston N, Jovanovic B, Flores F, et al.
Cancer Res
. 2019 Jun;
79(16):4173-4183.
PMID: 31239270
To define transcriptional dependencies of triple-negative breast cancer (TNBC), we identified transcription factors highly and specifically expressed in primary TNBCs and tested their requirement for cell growth in a panel...
8.
Pasala C, Chilamakuri C, Katari S, Nalamolu R, Bitla A, Amineni U
J Biomol Struct Dyn
. 2018 Dec;
37(14):3740-3750.
PMID: 30580658
The developing potent vaccine is a pre-emptive strategy to tackle drug abuses and maladies of multidrug-resistant strains. Ongoing vaccine studies are being conducted, however, development is in its infancy as...
9.
Tomic G, Morrissey E, Kozar S, Ben-Moshe S, Hoyle A, Azzarelli R, et al.
Cell Stem Cell
. 2018 Aug;
23(3):436-443.e7.
PMID: 30100168
The intestinal epithelium is largely maintained by self-renewing stem cells but with apparently committed progenitors also contributing, particularly following tissue damage. However, the mechanism of, and requirement for, progenitor plasticity...
10.
Papachristou E, Kishore K, Holding A, Harvey K, Roumeliotis T, Chilamakuri C, et al.
Nat Commun
. 2018 Jun;
9(1):2311.
PMID: 29899353
Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering disease mechanisms. To enable the in-depth analysis of protein interactions in chromatin-associated protein complexes, we have...