Chandra M V Goparaju
Overview
Explore the profile of Chandra M V Goparaju including associated specialties, affiliations and a list of published articles.
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7
Citations
195
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Recent Articles
1.
Mathur A, Blais S, Goparaju C, Neubert T, Pass H, Levon K
PLoS One
. 2013 Mar;
8(3):e57681.
PMID: 23516416
Hyaluronan-linked protein 1 (HAPLN1) which has been shown to be highly expressed in malignant pleural mesotheliomas (MPM), was detected in serum using an electrochemical surface-imprinting method. First, the detection method...
2.
Goparaju C, Pass H, Blasberg J, Hirsch N, Donington J
J Thorac Oncol
. 2010 Aug;
5(10):1516-23.
PMID: 20689445
Introduction: Osteopontin (OPN) is a multifunctional protein with an important but poorly understood role in non-small cell lung cancer (NSCLC) pathogenesis. Moreover, the role of the three known mRNA isoforms...
3.
Ivanov S, Goparaju C, Lopez P, Zavadil J, Toren-Haritan G, Rosenwald S, et al.
J Biol Chem
. 2010 May;
285(30):22809-17.
PMID: 20463022
The human genome encodes several hundred microRNA (miRNA) genes that produce small (21-23n) single strand regulatory RNA molecules. Although abnormal expression of miRNAs has been linked to cancer progression, the...
4.
Ivanova A, Goparaju C, Ivanov S, Nonaka D, Cruz C, Beck A, et al.
Clin Cancer Res
. 2009 Apr;
15(8):2602-11.
PMID: 19351750
Purpose: Tumor extracellular matrix (ECM) plays a crucial role in cancer progression mediating and transforming host-tumor interactions. Targeting the ECM is becoming an increasingly promising therapeutic approach in cancer treatment....
5.
Ivanov S, Ivanova A, Goparaju C, Chen Y, Beck A, Pass H
Biochem Biophys Res Commun
. 2009 Mar;
382(3):514-8.
PMID: 19285954
Osteopontin (SPP1) is an inflammatory cytokine that we previously characterized as a diagnostic marker in patients with asbestos-induced malignant mesothelioma (MM). While SPP1 shows both pro- and anti-tumorigenic biological effects,...
6.
Lu I, Huang C, Peng Y, Lin Y, Hsieh H, Chen C, et al.
J Med Chem
. 2006 Apr;
49(9):2703-12.
PMID: 16640330
Peroxisome proliferator-activated receptor gamma (PPARgamma) is well-known as the receptor of thiazolidinedione antidiabetic drugs. In this paper, we present a successful example of employing structure-based virtual screening, a method that...
7.
Mahindroo N, Huang C, Peng Y, Wang C, Liao C, Lien T, et al.
J Med Chem
. 2005 Dec;
48(26):8194-208.
PMID: 16366601
The synthesis and structure-activity relationship studies of novel indole derivatives as peroxisome proliferator-activated receptor (PPAR) agonists are reported. Indole, a drug-like scaffold, was studied as a core skeleton for the...