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Chandan Thomas

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Articles 7
Citations 186
Followers 0
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Recent Articles
1.
Thomas C, Rawat A, Hope-Weeks L, Ahsan F
Mol Pharm . 2010 Dec; 8(2):405-15. PMID: 21189035
Porous poly(L-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) nanoparticles were tested for pulmonary delivery of hepatitis B vaccine. In particular, the effects of particle size and hydrophobicity on mucosal and...
2.
Thomas C, Gupta V, Ahsan F
Pharm Res . 2010 Mar; 27(5):905-19. PMID: 20232117
Purpose: To test the hypothesis that particle size influences the magnitude of immune response produced by hepatitis B surface antigen (HBsAg) encapsulated in poly (lactic-co-glycolic acid) (PLGA) microspheres. Methods: Microspheres...
3.
Thomas C, Moridani M
Toxicology . 2009 Oct; 278(2):204-10. PMID: 19837123
A number of currently available vaccines have shown significant differences in the magnitude of immune responses and toxicity in individuals undergoing vaccination. A number of factors may be involved in...
4.
Thomas C, Gupta V, Ahsan F
Int J Pharm . 2009 Jun; 379(1):41-50. PMID: 19524654
This study investigates the efficacy of surface-modified microspheres of hepatitis B surface antigen (HBsAg) in eliciting systemic and mucosal immune responses. Positively charged poly(D,L-lactic-co-glycolic acid) microspheres were prepared by a...
5.
Thomas C, Rawat A, Bai S, Ahsan F
J Pharm Sci . 2007 Sep; 97(3):1213-23. PMID: 17828746
This study was designed to test the hypothesis that formulation of hepatitis B vaccine with tetradecyl-beta-maltoside (TDM) enhances the immune response after pulmonary administration in a rodent model. Commercially available...
6.
Bai S, Thomas C, Rawat A, Ahsan F
Crit Rev Ther Drug Carrier Syst . 2007 Apr; 23(6):437-95. PMID: 17425500
A large number of drug delivery systems--mostly in the form of liposomes, microspheres, nanoparticles and hydrogels--have been designed to achieve targeted delivery and sustained release of drugs by exploiting the...
7.
Bai S, Thomas C, Ahsan F
J Pharm Sci . 2007 Feb; 96(8):2090-106. PMID: 17286291
This study was designed to test the hypothesis that positively charged dendrimers form a complex with enoxaparin, a low-molecular weight heparin (LMWH), and that the resulting drug-dendrimer complex is effective...