Chad Torrice
Overview
Explore the profile of Chad Torrice including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
2713
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Recent Articles
11.
INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis
Liu Y, Sanoff H, Cho H, Burd C, Torrice C, Mohlke K, et al.
PLoS One
. 2009 Apr;
4(4):e5027.
PMID: 19343170
Background: Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2...
12.
Ji H, Ramsey M, Hayes D, Fan C, McNamara K, Kozlowski P, et al.
Nature
. 2007 Aug;
448(7155):807-10.
PMID: 17676035
Germline mutation in serine/threonine kinase 11 (STK11, also called LKB1) results in Peutz-Jeghers syndrome, characterized by intestinal hamartomas and increased incidence of epithelial cancers. Although uncommon in most sporadic cancers,...
13.
Ramsey M, Krishnamurthy J, Pei X, Torrice C, Lin W, Carrasco D, et al.
Cancer Res
. 2007 May;
67(10):4732-41.
PMID: 17510401
Cell cycle progression from G(1) to S phase depends on phosphorylation of pRb by complexes containing a cyclin (D type or E type) and cyclin-dependent kinase (e.g., cdk2, cdk4, or...
14.
Shields J, Thomas N, Cregger M, Berger A, Leslie M, Torrice C, et al.
Cancer Res
. 2007 Feb;
67(4):1502-12.
PMID: 17308088
The majority of human melanomas harbor activating mutations of either N-RAS or its downstream effector B-RAF, which cause activation of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) kinase and the...
15.
Penland S, Keku T, Torrice C, He X, Krishnamurthy J, Hoadley K, et al.
Lab Invest
. 2007 Feb;
87(4):383-91.
PMID: 17297435
RNA expression analysis is an important tool in cancer research, but a limitation has been the requirement for high-quality RNA, generally derived from frozen samples. Such tumor sets are often...
16.
Krishnamurthy J, Ramsey M, Ligon K, Torrice C, Koh A, Bonner-Weir S, et al.
Nature
. 2006 Sep;
443(7110):453-7.
PMID: 16957737
The p16INK4a tumour suppressor accumulates in many tissues as a function of advancing age. p16INK4a is an effector of senescence and a potent inhibitor of the proliferative kinase Cdk4 (ref....
17.
Krishnamurthy J, Torrice C, Ramsey M, Kovalev G, Al-Regaiey K, Su L, et al.
J Clin Invest
. 2004 Nov;
114(9):1299-307.
PMID: 15520862
The Ink4a/Arf locus encodes 2 tumor suppressor molecules, p16INK4a and Arf, which are principal mediators of cellular senescence. To study the links between senescence and aging in vivo, we examined...