Ceri A Roberts
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Explore the profile of Ceri A Roberts including associated specialties, affiliations and a list of published articles.
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7
Citations
341
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Recent Articles
1.
Ridley M, Fleskens V, Roberts C, Lalnunhlimi S, Alnesf A, OByrne A, et al.
J Immunol
. 2020 Apr;
204(11):2940-2948.
PMID: 32321757
The expression of anti-inflammatory IL-10 by CD4 T cells is indispensable for immune homeostasis, as it allows T cells to moderate their effector function. We previously showed that TNF-α blockade...
2.
Povoleri G, Lalnunhlimi S, Steel K, Agrawal S, OByrne A, Ridley M, et al.
Eur J Immunol
. 2019 Nov;
50(3):445-458.
PMID: 31722123
TNF-blockade has shown clear therapeutic value in rheumatoid arthritis and other immune-mediated inflammatory diseases, however its mechanism of action is not fully elucidated. We investigated the effects of TNF-blockade on...
3.
Perucha E, Melchiotti R, Bibby J, Wu W, Frederiksen K, Roberts C, et al.
Nat Commun
. 2019 Feb;
10(1):498.
PMID: 30700717
The mechanisms controlling CD4 T cell switching from an effector to an anti-inflammatory (IL-10) phenotype play an important role in the persistence of chronic inflammatory diseases. Here, we identify the...
4.
Roberts C, Durham L, Fleskens V, Evans H, Taams L
Front Immunol
. 2017 Mar;
8:157.
PMID: 28261215
CD4 and CD8 effector T cell subpopulations can display regulatory potential characterized by expression of the prototypically anti-inflammatory cytokine IL-10. However, the underlying cellular mechanisms that regulate expression of IL-10...
5.
Woollard W, Pullabhatla V, Lorenc A, Patel V, Butler R, Bayega A, et al.
Blood
. 2016 Apr;
127(26):3387-97.
PMID: 27121473
Sézary syndrome (SS) is a leukemic variant of cutaneous T-cell lymphoma (CTCL) and represents an ideal model for study of T-cell transformation. We describe whole-exome and single-nucleotide polymorphism array-based copy...
6.
Roberts C, Dickinson A, Taams L
Front Immunol
. 2015 Dec;
6:571.
PMID: 26635790
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation of the synovial lining (synovitis). The inflammation in the RA joint is associated with and driven by immune cell...
7.
Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, et al.
Nat Commun
. 2014 Feb;
5:3199.
PMID: 24492460
IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor (TNFi) drugs induce the anti-inflammatory cytokine IL-10 in CD4+ T...