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Celia McLean

Explore the profile of Celia McLean including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Keppie S, Mansfield J, Tang X, Philp C, Graham H, Onnerfjord P, et al.
Function (Oxf) . 2021 Aug; 2(5):zqab037. PMID: 34423304
Significance Statement: Osteoarthritis is the most prevalent musculoskeletal disease, affecting 250 million people worldwide. We identify a novel intrinsic repair response in cartilage, mediated by aggrecan-dependent sodium flux, and dependent...
2.
Tang X, Muhammad H, McLean C, Miotla-Zarebska J, Fleming J, Didangelos A, et al.
Ann Rheum Dis . 2018 Jun; 77(9):1372-1380. PMID: 29925506
Objectives: One mechanism by which cartilage responds to mechanical load is by releasing heparin-bound growth factors from the pericellular matrix (PCM). By proteomic analysis of the PCM, we identified connective...
3.
Chia S, Sawaji Y, Burleigh A, McLean C, Inglis J, Saklatvala J, et al.
Arthritis Rheum . 2009 Jul; 60(7):2019-27. PMID: 19565481
Objective: We have previously identified in articular cartilage an abundant pool of the heparin-binding growth factor, fibroblast growth factor 2 (FGF-2), which is bound to the pericellular matrix heparan sulfate...