Cedric S Raine
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Explore the profile of Cedric S Raine including associated specialties, affiliations and a list of published articles.
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91
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5202
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Recent Articles
11.
Chapouly C, Argaw A, Horng S, Castro K, Zhang J, Asp L, et al.
Brain
. 2015 Mar;
138(Pt 6):1548-67.
PMID: 25805644
In inflammatory central nervous system conditions such as multiple sclerosis, breakdown of the blood-brain barrier is a key event in lesion pathogenesis, predisposing to oedema, excitotoxicity, and ingress of plasma...
12.
Galazka G, Jurewicz A, Domowicz M, Cannella B, Raine C, Selmaj K
Eur J Immunol
. 2014 Aug;
44(10):3026-44.
PMID: 25092109
Heat shock proteins (Hsps) interact with the immune system and have been shown to contribute to immunoregulation. As efficient chaperones, Hsps bind many peptides and these complexes have many yet-to-be-clarified...
13.
Mycko M, Sliwinska B, Cichalewska M, Cwiklinska H, Raine C, Selmaj K
J Neurosci
. 2014 Jun;
34(25):8646-58.
PMID: 24948818
The CNS is considered an immune privileged site because its repertoire of highly immunogenic molecules remains unseen by the immune system under normal conditions. However, the mechanism underlying the inhibition...
14.
15.
OGuin K, Gruber R, Raine C, Guzik H, Poulos B, Shafit-Zagardo B
ASN Neuro
. 2014 Jan;
6(1):e00135.
PMID: 24476104
The molecular requirements for human myelination are incompletely defined, and further study is needed to fully understand the cellular mechanisms involved during development and in demyelinating diseases. We have established...
16.
Rusielewicz T, Nam J, Damanakis E, John G, Raine C, Melendez-Vasquez C
Glia
. 2014 Jan;
62(4):580-91.
PMID: 24470341
The oligodendrocyte (OL), the myelinating cell of the central nervous system, undergoes dramatic changes in the organization of its cytoskeleton as it differentiates from a precursor (oligodendrocyte precursor cells) to...
17.
Brosnan C, Raine C
Glia
. 2013 Jan;
61(4):453-65.
PMID: 23322421
Among the constituent cell types of the multiple sclerosis (MS) plaque, the astrocyte has been the least considered as a player in the pathogenesis of the lesion. Traditionally, it has...
18.
Han M, Lundgren D, Jaiswal S, Chao M, Graham K, Garris C, et al.
J Exp Med
. 2012 Jun;
209(7):1325-34.
PMID: 22734047
Comparison of transcriptomic and proteomic data from pathologically similar multiple sclerosis (MS) lesions reveals down-regulation of CD47 at the messenger RNA level and low abundance at the protein level. Immunohistochemical...
19.
Mycko M, Brosnan C, Raine C, Fendler W, Selmaj K
J Neurosci Res
. 2012 Jun;
90(10):1941-8.
PMID: 22715030
Heat shock proteins (HSPs) are stress-responsive proteins that serve as important molecules contributing to cellular "protein triage." We and others have reported an increase of selected HSPs in multiple sclerosis...
20.
Eugenin E, Basilio D, Saez J, Orellana J, Raine C, Bukauskas F, et al.
J Neuroimmune Pharmacol
. 2012 Mar;
7(3):499-518.
PMID: 22438035
Gap junctions (GJs) are expressed in most cell types of the nervous system, including neuronal stem cells, neurons, astrocytes, oligodendrocytes, cells of the blood brain barrier (endothelial cells and astrocytes)...