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Catia Traversari

Explore the profile of Catia Traversari including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 2722
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Recent Articles
1.
Raccosta L, Marinozzi M, Costantini S, Maggioni D, Ferreira L, Corna G, et al.
Cell Death Dis . 2023 Feb; 14(2):129. PMID: 36792589
Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic...
2.
Stornaiuolo A, Valentinis B, Sirini C, Scavullo C, Asperti C, Zhou D, et al.
Hum Gene Ther . 2021 Feb; 32(13-14):744-760. PMID: 33554732
Effectiveness of adoptively transferred chimeric antigen receptor (CAR) T cells strongly depends on the quality of CAR-mediated interaction of the effector cells with the target antigen on tumor cells. A...
3.
Porcellini S, Asperti C, Corna S, Cicoria E, Valtolina V, Stornaiuolo A, et al.
Front Immunol . 2020 Mar; 11:99. PMID: 32117253
The main challenge of adoptive therapy with Chimeric Antigen Receptor modified T cells (CAR T) is the application to the field of solid tumors, where the identification of a proper...
4.
Valentinis B, Porcellini S, Asperti C, Cota M, Zhou D, Di Matteo P, et al.
Int J Mol Sci . 2019 Sep; 20(18). PMID: 31547231
NGR-hTNF is a therapeutic agent for a solid tumor that specifically targets angiogenic tumor blood vessels, through the NGR motif. Its activity has been assessed in several clinical studies encompassing...
5.
Nardelli F, Paissoni C, Quilici G, Gori A, Traversari C, Valentinis B, et al.
J Med Chem . 2018 Jun; 61(17):7474-7485. PMID: 29883545
The isoDGR sequence is an integrin-binding motif that has been successfully employed as a tumor-vasculature-homing molecule or for the targeted delivery of drugs and diagnostic agents to tumors. In this...
6.
Norelli M, Camisa B, Barbiera G, Falcone L, Purevdorj A, Genua M, et al.
Nat Med . 2018 May; 24(6):739-748. PMID: 29808007
In the clinic, chimeric antigen receptor-modified T (CAR T) cell therapy is frequently associated with life-threatening cytokine-release syndrome (CRS) and neurotoxicity. Understanding the nature of these pathologies and developing treatments...
7.
Casucci M, Falcone L, Camisa B, Norelli M, Porcellini S, Stornaiuolo A, et al.
Front Immunol . 2018 Apr; 9:507. PMID: 29619024
Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization...
8.
Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, et al.
Proc Natl Acad Sci U S A . 2016 Sep; 113(41):E6219-E6227. PMID: 27671648
Cells in the tumor microenvironment may be reprogrammed by tumor-derived metabolites. Cholesterol-oxidized products, namely oxysterols, have been shown to favor tumor growth directly by promoting tumor cell growth and indirectly...
9.
Lanterna C, Musumeci A, Raccosta L, Corna G, Moresco M, Maggioni D, et al.
Cancer Immunol Immunother . 2016 Aug; 65(11):1303-1315. PMID: 27520505
Tumor-derived metabolites dampen tumor-infiltrating immune cells and antitumor immune responses. Among the various metabolites produced by tumors, we recently showed that cholesterol oxidized products, namely oxysterols, favor tumor growth through...
10.
Traversari C, Russo V
Methods Mol Biol . 2016 Apr; 1393:97-104. PMID: 27033219
The exploitation of the physiologic processing and presenting machinery of dendritic cells (DCs) by in vivo loading of tumor-associated antigens may improve the immunogenic potential and clinical efficacy of DC-based...