Catherine C Hedrick
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Explore the profile of Catherine C Hedrick including associated specialties, affiliations and a list of published articles.
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120
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9378
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Recent Articles
21.
Pandori W, Padgett L, Alimadadi A, Gutierrez N, Araujo D, Huh C, et al.
J Leukoc Biol
. 2022 Jul;
112(5):1053-1063.
PMID: 35866369
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in severe immune dysfunction, hospitalization, and death. Many patients also develop long-COVID-19, experiencing symptoms...
22.
Olingy C, Alimadadi A, Araujo D, Barry D, Gutierrez N, Werbin M, et al.
Front Immunol
. 2022 May;
13:842653.
PMID: 35493454
Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related deaths globally. Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti-programmed cell death protein 1 (anti-PD-1) therapy now...
23.
Orecchioni M, Meyer M, Hedrick C, Ley K
Methods Mol Biol
. 2022 Mar;
2419:779-800.
PMID: 35238001
Atherosclerosis is characterized by the abundant infiltration of immune cells starting at early stages and progressing to late stages of the disease. The study and characterization of immune cells infiltrating...
24.
Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice
Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, et al.
J Immunol
. 2022 Jan;
208(3):745-752.
PMID: 35031577
Cystic fibrosis (CF) is an inherited life-threatening disease accompanied by repeated lung infections and multiorgan inflammation that affects tens of thousands of people worldwide. The causative gene, cystic fibrosis transmembrane...
25.
Dinh H, Pan F, Wang G, Huang Q, Olingy C, Wu Z, et al.
Nat Commun
. 2021 Dec;
12(1):7335.
PMID: 34921160
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which shape cancer biology and impact the responsiveness to therapy. Here, we analyze the microenvironment of esophageal squamous...
26.
Gaddis D, Padgett L, Wu R, Nguyen A, McSkimming C, Dinh H, et al.
Arterioscler Thromb Vasc Biol
. 2021 Jul;
41(9):2387-2398.
PMID: 34320835
Objective: CD4 T cells are important regulators of atherosclerotic progression. The metabolic profile of CD4 T cells controls their signaling and function, but how atherosclerosis affects T-cell metabolism is unknown....
27.
Hedrick C, Malanchi I
Nat Rev Immunol
. 2021 Jul;
22(3):173-187.
PMID: 34230649
Neutrophils are the most abundant myeloid cells in human blood and are emerging as important regulators of cancer. However, their functional importance has often been overlooked on the basis that...
28.
Johnson J, Ramadass M, Rahman F, Meneses-Salas E, Zgajnar N, Carvalho Gontijo R, et al.
J Leukoc Biol
. 2021 Jun;
110(4):629-649.
PMID: 34085299
Despite the important function of neutrophils in the eradication of infections and induction of inflammation, the molecular mechanisms regulating the activation and termination of the neutrophil immune response is not...
29.
Padgett L, Dinh H, Wu R, Gaddis D, Araujo D, Winkels H, et al.
Arterioscler Thromb Vasc Biol
. 2020 Oct;
40(12):2845-2859.
PMID: 33054398
Objective: Cardiovascular disease (CVD) remains a significant global health concern with a high degree of mortality. While CD4 T cells have been extensively studied in CVD, the importance of CD8...
30.
Zhu Y, Eggert T, Araujo D, Vijayanand P, Ottensmeier C, Hedrick C
J Immunother Cancer
. 2020 Sep;
8(2).
PMID: 32912924
Background: Understanding neutrophil heterogeneity and its relationship to disease progression has become a recent focus of cancer research. Indeed, several studies have identified neutrophil subpopulations associated with protumoral or antitumoral...