Cassie L Kemmler
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Explore the profile of Cassie L Kemmler including associated specialties, affiliations and a list of published articles.
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7
Citations
36
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Recent Articles
1.
Lalonde R, Wells H, Kemmler C, Nieuwenhuize S, Lerma R, Burger A, et al.
Sci Adv
. 2024 Jun;
10(23):eadn6603.
PMID: 38838146
Standard zebrafish transgenesis involves random transgene integration with resource-intensive screening. While phiC31 integrase-based / recombination has streamlined transgenesis in mice and , validated -based landing sites for universal applications are...
2.
Lalonde R, Wells H, Kemmler C, Nieuwenhuize S, Lerma R, Burger A, et al.
bioRxiv
. 2023 Dec;
PMID: 38106217
Standard methods for transgenesis in zebrafish depend on random transgene integration into the genome followed by resource-intensive screening and validation. Targeted vector integration into validated genomic loci using phiC31 integrase-based...
3.
Kemmler C, Smolikova J, Moran H, Mannion B, Knapp D, Lim F, et al.
Nat Commun
. 2023 Oct;
14(1):6594.
PMID: 37852970
The cell type-specific expression of key transcription factors is central to development and disease. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, how its...
4.
Kemmler C, Smolikova J, Moran H, Mannion B, Knapp D, Lim F, et al.
bioRxiv
. 2023 May;
PMID: 37131681
The cell type-specific expression of key transcription factors is central to development. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, how its expression is...
5.
Kemmler C, Moran H, Murray B, Scoresby A, Klem J, Eckert R, et al.
Development
. 2023 Mar;
150(8).
PMID: 36975217
Transgenesis is an essential technique for any genetic model. Tol2-based transgenesis paired with Gateway-compatible vector collections has transformed zebrafish transgenesis with an accessible modular system. Here, we establish several next-generation...
6.
Lalonde R, Kemmler C, Riemslagh F, Aman A, Kresoja-Rakic J, Moran H, et al.
Dev Dyn
. 2022 May;
251(10):1754-1773.
PMID: 35582941
Background: The most-common strategy for zebrafish Cre/lox-mediated lineage labeling experiments combines ubiquitously expressed, lox-based Switch reporter transgenes with tissue-specific Cre or 4-OH-Tamoxifen-inducible CreERT2 driver lines. Although numerous Cre driver lines...
7.
Kemmler C, Riemslagh F, Moran H, Mosimann C
J Cardiovasc Dev Dis
. 2021 Feb;
8(2).
PMID: 33578943
The heart is the first functional organ to form during vertebrate development. Congenital heart defects are the most common type of human birth defect, many originating as anomalies in early...