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Carsten Enggaard Stidsen

Explore the profile of Carsten Enggaard Stidsen including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 189
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Recent Articles
1.
Polex-Wolf J, Deibler K, Hogendorf W, Bau S, Glendorf T, Stidsen C, et al.
Sci Transl Med . 2024 Dec; 16(776):eadk4908. PMID: 39630884
Glucagon-like peptide-1 (GLP-1) and leptin signal recent feeding and long-term energy stores, respectively, and play complementary roles in the modulation of energy balance. Previous work using single-cell techniques in mice...
2.
Smidt J, Lykke L, Stidsen C, Pristovsek N, Gothelf K
Nucleic Acids Res . 2023 Nov; 52(1):49-58. PMID: 37971296
Conjugates of therapeutic oligonucleotides (ONs) including peptide conjugates, provide a potential solution to the major challenge of specific tissue delivery faced by this class of drugs. Conjugations are often positioned...
3.
Nishimura E, Pridal L, Glendorf T, Hansen B, Hubalek F, Kjeldsen T, et al.
BMJ Open Diabetes Res Care . 2021 Aug; 9(1). PMID: 34413118
Introduction: Insulin icodec is a novel, long-acting insulin analog designed to cover basal insulin requirements with once-weekly subcutaneous administration. Here we describe the molecular engineering and the biological and pharmacological...
4.
Hubalek F, Refsgaard H, Gram-Nielsen S, Madsen P, Nishimura E, Munzel M, et al.
Nat Commun . 2021 Jul; 11(1):4232. PMID: 34244486
No abstract available.
5.
Jensen A, Hubalek F, Stidsen C, Johansson E, Oberg F, Skjot M, et al.
Protein Expr Purif . 2021 Jun; 186:105910. PMID: 34089870
Expression of recombinant proteins traditionally require a cellular system to transcribe and translate foreign DNA to a desired protein. The process requires special knowledge of the specific cellular metabolism in...
6.
Hubalek F, Refsgaard H, Gram-Nielsen S, Madsen P, Nishimura E, Munzel M, et al.
Nat Commun . 2020 Jul; 11(1):3746. PMID: 32719315
Recently, the clinical proof of concept for the first ultra-long oral insulin was reported, showing efficacy and safety similar to subcutaneously administered insulin glargine. Here, we report the molecular engineering...
7.
Hansen B, Glendorf T, Hegelund A, Lundby A, Lutzen A, Slaaby R, et al.
PLoS One . 2012 May; 7(5):e34274. PMID: 22590494
Aims/hypothesis: There is controversy with respect to molecular characteristics of insulin analogues. We report a series of experiments forming a comprehensive characterisation of the long acting insulin analogues, glargine and...
8.
Moller L, Stidsen C, Hartmann B, Holst J
Biochim Biophys Acta . 2003 Sep; 1616(1):1-84. PMID: 14507421
In 1972, Brazeau et al. isolated somatostatin (somatotropin release-inhibiting factor, SRIF), a cyclic polypeptide with two biologically active isoforms (SRIF-14 and SRIF-28). This event prompted the successful quest for SRIF...