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Carolyn R Morris

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Articles 12
Citations 172
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Recent Articles
1.
Tharp W, Morris C, Santos-Ortega Y, Vary C, Bender S, Dixon A
Am J Physiol Lung Cell Mol Physiol . 2024 Sep; 327(5):L615-L623. PMID: 39254086
Obesity may lead to pulmonary dysfunction through complex and incompletely understood cellular and biochemical effects. Altered lung lipid metabolism has been identified as a potential mechanism of lung dysfunction in...
2.
Chandrasekaran R, Morris C, Butzirus I, Mark Z, Kumar A, Souza De Lima D, et al.
Front Pharmacol . 2023 Sep; 14:1248873. PMID: 37680710
Obesity is a risk factor for severe influenza, and asthma exacerbations caused by respiratory viral infections. We investigated mechanisms that increase the severity of airway disease related to influenza in...
3.
Habibovic A, Hristova M, Morris C, Lin M, Cruz L, Ather J, et al.
Am J Physiol Lung Cell Mol Physiol . 2023 Jan; 324(2):L228-L242. PMID: 36625485
More than 50% of people with asthma in the United States are obese, and obesity often worsens symptoms of allergic asthma and impairs response to treatment. Based on previously established...
4.
Chandrasekaran R, Bruno S, Mark Z, Walzer J, Caffry S, Gold C, et al.
Am J Physiol Lung Cell Mol Physiol . 2022 Dec; 324(2):L141-L153. PMID: 36511516
Obesity is associated with severe, difficult-to-control asthma, and increased airway oxidative stress. Mitochondrial reactive oxygen species (mROS) are an important source of oxidative stress in asthma, leading us to hypothesize...
5.
Morris C, Habibovic A, Dustin C, Schiffers C, Lin M, Ather J, et al.
Mucosal Immunol . 2022 Jun; 15(5):977-989. PMID: 35654836
The NADPH oxidase DUOX1 contributes to epithelial production of alarmins, including interleukin (IL)-33, in response to injurious triggers such as airborne protease allergens, and mediates development of mucus metaplasia and...
6.
Dustin C, Habibovic A, Hristova M, Schiffers C, Morris C, Lin M, et al.
J Immunol . 2021 Jun; 206(12):2989-2999. PMID: 34088769
The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these...
7.
Faherty C, Wu T, Morris C, Grassel C, Rasko D, Harper J, et al.
Gut Microbes . 2016 Sep; 7(6):486-502. PMID: 27657187
Shigella flexneri is a Gram-negative pathogen that invades the colonic epithelium and causes millions of cases of watery diarrhea or bacillary dysentery predominately in children under the age of 5 ...
8.
Sahl J, Morris C, Emberger J, Fraser C, Ochieng J, Juma J, et al.
J Clin Microbiol . 2015 Jan; 53(3):951-60. PMID: 25588655
Shigellae cause significant diarrheal disease and mortality in humans, as there are approximately 163 million episodes of shigellosis and 1.1 million deaths annually. While significant strides have been made in...
9.
Morris C, Grassel C, Redman J, Sahl J, Barry E, Rasko D
Infect Immun . 2013 Jun; 81(9):3068-76. PMID: 23753632
Shigella species Gram-negative bacteria which cause a diarrheal disease, known as shigellosis, by invading and destroying the colonic mucosa and inducing a robust inflammatory response. With no vaccine available, shigellosis...
10.
Lindsay B, Ochieng J, Ikumapayi U, Toure A, Ahmed D, Li S, et al.
J Clin Microbiol . 2013 Mar; 51(6):1740-6. PMID: 23536399
Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in...