Aida Habibovic
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Explore the profile of Aida Habibovic including associated specialties, affiliations and a list of published articles.
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21
Citations
496
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Recent Articles
1.
Cruz L, Habibovic A, Dempsey B, Massafera M, Janssen-Heininger Y, Lin M, et al.
Redox Biol
. 2024 Mar;
71:103102.
PMID: 38430684
Peroxidasin (PXDN) is a secreted heme peroxidase that catalyzes the oxidative crosslinking of collagen IV within the extracellular matrix (ECM) via intermediate hypobromous acid (HOBr) synthesis from hydrogen peroxide and...
2.
Habibovic A, Hristova M, Morris C, Lin M, Cruz L, Ather J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Jan;
324(2):L228-L242.
PMID: 36625485
More than 50% of people with asthma in the United States are obese, and obesity often worsens symptoms of allergic asthma and impairs response to treatment. Based on previously established...
3.
Morris C, Habibovic A, Dustin C, Schiffers C, Lin M, Ather J, et al.
Mucosal Immunol
. 2022 Jun;
15(5):977-989.
PMID: 35654836
The NADPH oxidase DUOX1 contributes to epithelial production of alarmins, including interleukin (IL)-33, in response to injurious triggers such as airborne protease allergens, and mediates development of mucus metaplasia and...
4.
Dustin C, Habibovic A, Hristova M, Schiffers C, Morris C, Lin M, et al.
J Immunol
. 2021 Jun;
206(12):2989-2999.
PMID: 34088769
The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these...
5.
Schiffers C, Lundblad L, Hristova M, Habibovic A, Dustin C, Daphtary N, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 May;
321(1):L144-L158.
PMID: 33951398
Aging is associated with a gradual loss of lung function due to increased cellular senescence, decreased regenerative capacity, and impaired innate host defense. One important aspect of innate airway epithelial...
6.
Veith C, Hristova M, Danyal K, Habibovic A, Dustin C, McDonough J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2020 Dec;
320(3):L356-L367.
PMID: 33325804
Idiopathic pulmonary fibrosis (IPF) is characterized by a disturbed redox balance and increased production of reactive oxygen species (ROS), which is believed to contribute to epithelial injury and fibrotic lung...
7.
Schiffers C, van de Wetering C, Bauer R, Habibovic A, Hristova M, Dustin C, et al.
JCI Insight
. 2020 Dec;
6(2).
PMID: 33301419
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by small airway remodeling and alveolar emphysema due to environmental stresses such as cigarette smoking (CS). Oxidative stress is...
8.
Schiffers C, Hristova M, Habibovic A, Dustin C, Danyal K, Reynaert N, et al.
Am J Respir Cell Mol Biol
. 2020 Mar;
63(2):198-208.
PMID: 32182090
The airway epithelium plays a critical role in innate responses to airborne allergens by secreting IL-1 family cytokines such as IL-1α and IL-33 as alarmins that subsequently orchestrate appropriate immune...
9.
Little A, Hristova M, van Lith L, Schiffers C, Dustin C, Habibovic A, et al.
Sci Rep
. 2019 Mar;
9(1):4844.
PMID: 30890751
Lung cancers are frequently characterized by inappropriate activation of epidermal growth factor receptor (EGFR)-dependent signaling and epigenetic silencing of the NADPH oxidase (NOX) enzyme DUOX1, both potentially contributing to worse...
10.
Habibovic A, Hristova M, Heppner D, Danyal K, Ather J, Janssen-Heininger Y, et al.
JCI Insight
. 2016 Nov;
1(18):e88811.
PMID: 27812543
Chronic inflammation with mucous metaplasia and airway remodeling are hallmarks of allergic asthma, and these outcomes have been associated with enhanced expression and activation of EGFR signaling. Here, we demonstrate...