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Nirav Daphtary

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Articles 30
Citations 381
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Recent Articles
1.
Kumar A, Mark Z, Carbajal M, DeLima D, Chamberlain N, Walzer J, et al.
Br J Pharmacol . 2024 Aug; 181(22):4610-4627. PMID: 39118388
Background And Purpose: Fibrotic lung remodelling after a respiratory viral infection represents a debilitating clinical sequela. Studying or managing viral-fibrotic sequela remains challenging, due to limited therapeutic options and lack...
2.
Chandrasekaran R, Morris C, Butzirus I, Mark Z, Kumar A, Souza De Lima D, et al.
Front Pharmacol . 2023 Sep; 14:1248873. PMID: 37680710
Obesity is a risk factor for severe influenza, and asthma exacerbations caused by respiratory viral infections. We investigated mechanisms that increase the severity of airway disease related to influenza in...
3.
Bruno S, Lamberty A, McCoy M, Mark Z, Daphtary N, Aliyeva M, et al.
Front Allergy . 2023 Jun; 4:1187945. PMID: 37377691
Mitochondria are multifaceted organelles necessary for numerous cellular signaling and regulatory processes. Mitochondria are dynamic organelles, trafficked and anchored to subcellular sites depending upon the cellular and tissue requirements. Precise...
4.
Chandrasekaran R, Bruno S, Mark Z, Walzer J, Caffry S, Gold C, et al.
Am J Physiol Lung Cell Mol Physiol . 2022 Dec; 324(2):L141-L153. PMID: 36511516
Obesity is associated with severe, difficult-to-control asthma, and increased airway oxidative stress. Mitochondrial reactive oxygen species (mROS) are an important source of oxidative stress in asthma, leading us to hypothesize...
5.
Ramcharran H, Bates J, Satalin J, Blair S, Andrews P, Gaver D, et al.
J Appl Physiol (1985) . 2022 Sep; 133(5):1093-1105. PMID: 36135956
Ventilator-induced lung injury (VILI) is a significant risk for patients with acute respiratory distress syndrome (ARDS). Management of the patient with ARDS is currently dominated by the use of low...
6.
Bhatawadekar S, Dixon A, Peters U, Daphtary N, Hodgdon K, Kaminsky D, et al.
J Appl Physiol (1985) . 2021 Oct; 131(6):1663-1670. PMID: 34647827
Late-onset nonallergic (LONA) asthma in obesity is characterized by increased peripheral airway closure secondary to abnormally collapsible airways. We hypothesized that positive expiratory pressure (PEP) would mitigate the tendency to...
7.
Bhatawadekar S, Peters U, Walsh R, Daphtary N, Maclean E, Hodgdon K, et al.
Ann Am Thorac Soc . 2021 Aug; 19(1):135-139. PMID: 34343031
No abstract available.
8.
Dustin C, Habibovic A, Hristova M, Schiffers C, Morris C, Lin M, et al.
J Immunol . 2021 Jun; 206(12):2989-2999. PMID: 34088769
The respiratory epithelium forms the first line of defense against inhaled pathogens and acts as an important source of innate cytokine responses to environmental insults. One critical mediator of these...
9.
Freeman K, Miller Z, Herrington R, Dreyfus N, Buttaravoli P, Burgess A, et al.
J Am Coll Emerg Physicians Open . 2021 May; 2(2):e12440. PMID: 33969347
Objective: No oropharyngeal devices exist for use in conscious and semiconscious trauma patients during emergency evacuation, transport, or resuscitation. We aimed to test the hypotheses that the ManMaxAirway (MMA) is...
10.
Schiffers C, Lundblad L, Hristova M, Habibovic A, Dustin C, Daphtary N, et al.
Am J Physiol Lung Cell Mol Physiol . 2021 May; 321(1):L144-L158. PMID: 33951398
Aging is associated with a gradual loss of lung function due to increased cellular senescence, decreased regenerative capacity, and impaired innate host defense. One important aspect of innate airway epithelial...