Caroline Lemieux
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Explore the profile of Caroline Lemieux including associated specialties, affiliations and a list of published articles.
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14
Citations
508
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Recent Articles
1.
Giovannoni G, Coyle P, Vermersch P, Walker B, Aldridge J, Nolting A, et al.
Front Immunol
. 2022 Jan;
12:763433.
PMID: 35003076
Cladribine tablets (CladT) preferentially reduce B and T lymphocyte levels. As aging is associated with a decline in immune function, the effect of CladT on lymphocyte levels may differ by...
2.
Ashton-Beaucage D, Lemieux C, Udell C, Sahmi M, Rochette S, Therrien M
PLoS Biol
. 2016 Aug;
14(8):e1002539.
PMID: 27552662
RAS-induced MAPK signaling is a central driver of the cell proliferation apparatus. Disruption of this pathway is widely observed in cancer and other pathologies. Consequently, considerable effort has been devoted...
3.
Lemieux C, Marguerat S, Lafontaine J, Barbezier N, Bahler J, Bachand F
Mol Cell
. 2011 Oct;
44(1):108-19.
PMID: 21981922
General discard pathways eliminate unprocessed and irregular pre-mRNAs to control the quality of gene expression. In contrast to such general pre-mRNA decay, we describe here a nuclear pre-mRNA degradation pathway...
4.
Tardif K, Cloutier I, Miao Z, Lemieux C, St-Denis C, Winnik F, et al.
Biomaterials
. 2011 May;
32(22):5046-55.
PMID: 21546078
The aim of the present study was to develop a new biopolymer to increase endothelial progenitor cells (EPC) survival and amplification. As a cell culture platform, bone marrow-derived cells (BMDC)...
5.
St-Andre O, Lemieux C, Perreault A, Lackner D, Bahler J, Bachand F
J Biol Chem
. 2010 Jul;
285(36):27859-68.
PMID: 20622014
Meiosis is a cellular differentiation process in which hundreds of genes are temporally induced. Because the expression of meiotic genes during mitosis is detrimental to proliferation, meiotic genes must be...
6.
Lemay J, Lemieux C, St-Andre O, Bachand F
RNA Biol
. 2010 Apr;
7(3):291-5.
PMID: 20400847
The addition of a 3' poly(A) tail is a pre-requisite for the maturation of the majority of eukaryotic transcripts. In most eukaryotic species, RNA poly(A) tails are bound by two...
7.
Lemay J, DAmours A, Lemieux C, Lackner D, St-Sauveur V, Bahler J, et al.
Mol Cell
. 2010 Feb;
37(1):34-45.
PMID: 20129053
Poly(A)-binding proteins (PABPs) are important to eukaryotic gene expression. In the nucleus, the PABP PABPN1 is thought to function in polyadenylation of pre-mRNAs. Deletion of fission yeast pab2, the homolog...
8.
Lemieux C, Bachand F
Nucleic Acids Res
. 2009 Apr;
37(10):3418-30.
PMID: 19336419
Synthesis of the pre-mRNA poly(A) tail in the nucleus has important consequences on the translational activity of the mature mRNA in the cytoplasm. In most eukaryotes, nuclear polyadenylation of pre-mRNAs...
9.
Lemieux C, Cloutier I, Tanguay J
Stem Cells Dev
. 2008 Nov;
17(6):1153-63.
PMID: 19006456
The recent interest in the role of bone marrow (BM)-derived endothelial progenitor cells (EPCs) and the benefits of estrogen on cardiovascular health brought us to evaluate if estrogen could affect...
10.
Lemieux C, Cloutier I, Tanguay J
Int J Cardiol
. 2008 Jul;
136(2):200-10.
PMID: 18644636
Background: The potential role of endothelial progenitor cells (EPCs) in the beneficial effects of estrogen on women's cardiovascular health is of great interest. We thus evaluated if menstrual cycle influences...