Carole A Sargent
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Explore the profile of Carole A Sargent including associated specialties, affiliations and a list of published articles.
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20
Citations
415
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Recent Articles
1.
Quilter C, Harvey K, Bauer J, Skinner B, Gomez M, Shrivastava M, et al.
FASEB Bioadv
. 2021 Apr;
3(4):205-230.
PMID: 33842847
Low birthweight and reduced height gain during infancy (stunting) may arise at least in part from adverse early life environments that trigger epigenetic reprogramming that may favor survival. We examined...
2.
Warr A, Affara N, Aken B, Beiki H, Bickhart D, Billis K, et al.
Gigascience
. 2020 Jun;
9(6).
PMID: 32543654
Background: The domestic pig (Sus scrofa) is important both as a food source and as a biomedical model given its similarity in size, anatomy, physiology, metabolism, pathology, and pharmacology to...
3.
Osei-Amponsah R, Skinner B, Adjei D, Bauer J, Larson G, Affara N, et al.
BMC Genomics
. 2017 Feb;
18(1):193.
PMID: 28219344
Background: The Ashanti Dwarf Pig (ADP) of Ghana is an endangered pig breed with hardy and disease resistant traits. Characterisation of animal genetic resources provides relevant data for their conservation...
4.
Skinner B, Sargent C, Churcher C, Hunt T, Herrero J, Loveland J, et al.
Genome Res
. 2015 Nov;
26(1):130-9.
PMID: 26560630
We have generated an improved assembly and gene annotation of the pig X Chromosome, and a first draft assembly of the pig Y Chromosome, by sequencing BAC and fosmid clones...
5.
Skinner B, Lachani K, Sargent C, Yang F, Ellis P, Hunt T, et al.
BMC Genomics
. 2015 Jun;
16:442.
PMID: 26055083
Background: Amplified gene families on sex chromosomes can harbour genes with important biological functions, especially relating to fertility. The Y-linked heat shock transcription factor (HSFY) family has become amplified on...
6.
Ellis P, Morris T, Skinner B, Sargent C, Vickers M, Gluckman P, et al.
BMC Genomics
. 2014 Jan;
15:49.
PMID: 24447410
Background: Maternal undernutrition leads to an increased risk of metabolic disorders in offspring including obesity and insulin resistance, thought to be due to a programmed thrifty phenotype which is inappropriate...
7.
Skinner B, Lachani K, Sargent C, Affara N
BMC Genet
. 2013 Jan;
14:3.
PMID: 23320497
Background: Sex chromosomes are subject to evolutionary pressures distinct from the remainder of the genome, shaping their structure and sequence content. We are interested in the sex chromosomes of domestic...
8.
Forsey K, Ellis P, Sargent C, Sturmey R, Leese H
Mol Reprod Dev
. 2013 Jan;
80(3):185-92.
PMID: 23280606
Creatine Kinase (CK) catalyses the "creatine shuttle," the reversible conversion of creatine phosphate to creatine with the liberation of ATP. This article examines the potential role of the creatine shuttle...
9.
Quilter C, Bagga M, Moinie A, Junaid F, Sargent C
BMC Neurosci
. 2012 Apr;
13:37.
PMID: 22471812
Background: The serotonin pathways have been implicated in behavioural phenotypes in a number of species, including human, rat, mouse, dog and chicken. Components of the pathways, including the receptors, are...
10.
Wilkinson J, Sargent C, Galina-Pantoja L, Tucker A
BMC Genomics
. 2010 Jul;
11:455.
PMID: 20670446
Background: Haemophilus parasuis is the causative agent of Glässer's disease in pigs. Currently, little is known about the molecular mechanisms that contribute to disease susceptibility. This study used a porcine...