Carlos Barcia
Overview
Explore the profile of Carlos Barcia including associated specialties, affiliations and a list of published articles.
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49
Citations
1313
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Recent Articles
1.
Zhao K, Calero-Perez P, Bopp M, Moschl V, Pagenstecher A, Mulero-Acevedo M, et al.
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139457
The tumor microenvironment in glioblastoma (GB) is considered to be "cold", i.e., the fraction of cytotoxic T cells, for instance, is low. Instead, macrophages are the major immune cell population...
2.
Portero-Tresserra M, Galofre-Lopez N, Pallares E, Gimenez-Montes C, Barcia C, Granero R, et al.
Nutrients
. 2023 Apr;
15(7).
PMID: 37049417
Age-related neurobiological changes significantly affect hippocampal structure and function, such that the main cognitive impairments associated with aging are related to the integrity of this brain structure, including the deterioration...
3.
Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells
Martinez-Escardo L, Alemany M, Sanchez-Osuna M, Sanchez-Chardi A, Roig-Martinez M, Suarez-Garcia S, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771741
Glioblastoma (GBM) is a highly aggressive brain tumor and almost all patients die because of relapses. GBM-derived cells undergo cell death without nuclear fragmentation upon treatment with different apoptotic agents....
4.
Cribaro G, Saavedra-Lopez E, Romarate L, Mitxitorena I, Diaz L, Casanova P, et al.
Acta Neuropathol Commun
. 2021 Feb;
9(1):24.
PMID: 33579378
The cellular complexity of glioblastoma microenvironments is still poorly understood. In-depth, cell-resolution tissue analyses of human material are rare but highly necessary to understand the biology of this deadly tumor....
5.
Conway G, Zizyte D, Mondala J, He Z, Lynam L, Lecourt M, et al.
Pharmaceuticals (Basel)
. 2021 Feb;
14(2).
PMID: 33530486
Ursolic acid (UA) is a bioactive compound which has demonstrated therapeutic efficacy in a variety of cancer cell lines. UA activates various signalling pathways in Glioblastoma multiforme (GBM) and offers...
6.
Saavedra-Lopez E, Roig-Martinez M, Cribaro G, Casanova P, Gallego J, Perez-Valles A, et al.
Brain Commun
. 2020 Sep;
2(1):fcz043.
PMID: 32954312
Hypoxic pseudopalisades are a pathological hallmark of human glioblastoma, which is linked to tumour malignancy and aggressiveness. Yet, their function and role in the tumour development have scarcely been explored....
7.
Conway G, He Z, Hutanu A, Cribaro G, Manaloto E, Casey A, et al.
Sci Rep
. 2019 Sep;
9(1):12891.
PMID: 31501494
Room temperature Cold Atmospheric Plasma (CAP) has shown promising efficacy for the treatment of cancer but the exact mechanisms of action remain unclear. Both apoptosis and necrosis have been implicated...
8.
Roig-Martinez M, Saavedra-Lopez E, Casanova P, Cribaro G, Barcia C
Results Probl Cell Differ
. 2019 Aug;
67:223-231.
PMID: 31435797
T cells effectively explore the tissue in search for antigens. When activated, they dedicate a big amount of energy and resources to arrange a complex structure called immunological synapse (IS),...
9.
He Z, Liu K, Manaloto E, Casey A, Cribaro G, Byrne H, et al.
Sci Rep
. 2018 Mar;
8(1):5298.
PMID: 29593309
Gold nanoparticles (AuNP) have potential as both diagnostic and therapeutic vehicles. However, selective targeting and uptake in cancer cells remains challenging. Cold atmospheric plasma (CAP) can be combined with AuNP...
10.
Cribaro G, Saavedra-Lopez E, Casanova P, Rodriguez L, Barcia C
Methods Mol Biol
. 2017 Mar;
1584:517-531.
PMID: 28255723
In this chapter, we describe the technical details to visualize and analyze effector immunological synapses between T cells and astrocytes in the brain with high-resolution confocal imaging. This procedure is...