Carlos Anerillas
Overview
Explore the profile of Carlos Anerillas including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
257
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Recent Articles
1.
Payea M, Dar S, Anerillas C, Martindale J, Belair C, Munk R, et al.
Mol Cell
. 2024 Oct;
84(22):4454-4469.e7.
PMID: 39481386
Senescence is a state of indefinite cell-cycle arrest associated with aging, cancer, and age-related diseases. Here, we find that translational deregulation, together with a corresponding maladaptive integrated stress response (ISR),...
2.
Occean J, Yang N, Sun Y, Dawkins M, Munk R, Belair C, et al.
Nat Commun
. 2024 Jul;
15(1):6357.
PMID: 39069555
DNA hydroxymethylation (5hmC), the most abundant oxidative derivative of DNA methylation, is typically enriched at enhancers and gene bodies of transcriptionally active and tissue-specific genes. Although aberrant genomic 5hmC has...
3.
Shin C, Rossi M, Anerillas C, Martindale J, Yang X, Ji E, et al.
Mol Cell Biol
. 2024 May;
44(5):194-208.
PMID: 38769646
Cellular senescence is a dynamic biological process triggered by sublethal cell damage and driven by specific changes in gene expression programs. We recently identified ANKRD1 (ankyrin repeat domain 1) as...
4.
Rossi M, Banskota N, Shin C, Anerillas C, Tsitsipatis D, Yang J, et al.
Nucleic Acids Res
. 2024 May;
52(12):7261-7278.
PMID: 38721764
RNA modifications, including N6-methyladenosine (m6A), critically modulate protein expression programs in a range of cellular processes. Although the transcriptomes of cells undergoing senescence are strongly regulated, the landscape and impact...
5.
Anerillas C, Perramon-Guell A, Altes G, Cuesta S, Vaquero M, Olomi A, et al.
Cell Death Dis
. 2024 Apr;
15(4):296.
PMID: 38670941
Genes of the Sprouty family (Spry1-4) restrain signaling by certain receptor tyrosine kinases. Consequently, these genes participate in several developmental processes and function as tumor suppressors in adult life. Despite...
6.
Li J, Krause G, Gui Q, Kaushik S, Rona G, Zhang Q, et al.
Sci Adv
. 2023 Oct;
9(41):eadh1134.
PMID: 37831778
Intracellular degradation of proteins and organelles by the autophagy-lysosome system is essential for cellular quality control and energy homeostasis. Besides degradation, endolysosomal organelles can fuse with the plasma membrane and...
7.
Deinhardt-Emmer S, Deshpande S, Kitazawa K, Herman A, Bons J, Rose J, et al.
Aging Dis
. 2023 Sep;
15(3):1398-1415.
PMID: 37728586
During cellular senescence, persistent growth arrest and changes in protein expression programs are accompanied by a senescence-associated secretory phenotype (SASP). In this study, we detected the upregulation of the SASP-related...
8.
Anerillas C, Mazan-Mamczarz K, Herman A, Munk R, Lam K, Calvo-Rubio M, et al.
Nat Aging
. 2023 Sep;
3(10):1237-1250.
PMID: 37667102
Sublethal cell damage can trigger senescence, a complex adaptive program characterized by growth arrest, resistance to apoptosis and a senescence-associated secretory phenotype (SASP). Here, a whole-genome CRISPR knockout screen revealed...
9.
Payea M, Dar S, Anerillas C, Martindale J, Belair C, Munk R, et al.
bioRxiv
. 2023 Aug;
PMID: 37609272
Senescence is a state of indefinite cell cycle arrest associated with aging, cancer, and age-related diseases. Here, using label-based mass spectrometry, ribosome profiling and nanopore direct RNA sequencing, we explore...
10.
Tsitsipatis D, Martindale J, Mazan-Mamczarz K, Herman A, Piao Y, Banskota N, et al.
Aging Cell
. 2023 Jul;
22(11):e13915.
PMID: 37462262
Changes in the transcriptomes of human tissues with advancing age are poorly cataloged. Here, we sought to identify the coding and long noncoding RNAs present in cultured primary skin fibroblasts...