Kotb Abdelmohsen
Overview
Explore the profile of Kotb Abdelmohsen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
156
Citations
13937
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Shin C, Rossi M, Mazan-Mamczarz K, Martindale J, Munk R, Pal A, et al.
Mol Cell Biol
. 2025 Jan;
45(3):129-141.
PMID: 39804141
Cellular senescence is a complex biological response to sublethal damage. The RNA-binding protein HNRNPK was previously found to decrease prominently during senescence in human diploid fibroblasts. Here, analysis of the...
2.
Payea M, Dar S, Anerillas C, Martindale J, Belair C, Munk R, et al.
Mol Cell
. 2024 Oct;
84(22):4454-4469.e7.
PMID: 39481386
Senescence is a state of indefinite cell-cycle arrest associated with aging, cancer, and age-related diseases. Here, we find that translational deregulation, together with a corresponding maladaptive integrated stress response (ISR),...
3.
Abdelmohsen K, Mazan-Mamczarz K, Munk R, Tsitsipatis D, Meng Q, Rossi M, et al.
Aging Cell
. 2024 Aug;
23(11):e14297.
PMID: 39143693
Cellular senescence, a state of persistent growth arrest, is closely associated with aging and age-related diseases. Deciphering the heterogeneity within senescent cell populations and identifying therapeutic targets are paramount for...
4.
Shin C, Rossi M, Anerillas C, Martindale J, Yang X, Ji E, et al.
Mol Cell Biol
. 2024 May;
44(5):194-208.
PMID: 38769646
Cellular senescence is a dynamic biological process triggered by sublethal cell damage and driven by specific changes in gene expression programs. We recently identified ANKRD1 (ankyrin repeat domain 1) as...
5.
Rossi M, Banskota N, Shin C, Anerillas C, Tsitsipatis D, Yang J, et al.
Nucleic Acids Res
. 2024 May;
52(12):7261-7278.
PMID: 38721764
RNA modifications, including N6-methyladenosine (m6A), critically modulate protein expression programs in a range of cellular processes. Although the transcriptomes of cells undergoing senescence are strongly regulated, the landscape and impact...
6.
Meng Q, Chen C, Yang N, Gololobova O, Shi C, Dunn C, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(43):e2219801120.
PMID: 37862381
Senescent cells are beneficial for repairing acute tissue damage, but they are harmful when they accumulate in tissues, as occurs with advancing age. Senescence-associated extracellular vesicles (S-EVs) can mediate cell-to-cell...
7.
Abdelmohsen K, Herman A, Carr A, Henry-Smith C, Rossi M, Meng Q, et al.
J Extracell Biol
. 2023 Sep;
2(8).
PMID: 37744304
Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of...
8.
Deinhardt-Emmer S, Deshpande S, Kitazawa K, Herman A, Bons J, Rose J, et al.
Aging Dis
. 2023 Sep;
15(3):1398-1415.
PMID: 37728586
During cellular senescence, persistent growth arrest and changes in protein expression programs are accompanied by a senescence-associated secretory phenotype (SASP). In this study, we detected the upregulation of the SASP-related...
9.
Anerillas C, Mazan-Mamczarz K, Herman A, Munk R, Lam K, Calvo-Rubio M, et al.
Nat Aging
. 2023 Sep;
3(10):1237-1250.
PMID: 37667102
Sublethal cell damage can trigger senescence, a complex adaptive program characterized by growth arrest, resistance to apoptosis and a senescence-associated secretory phenotype (SASP). Here, a whole-genome CRISPR knockout screen revealed...
10.
Payea M, Dar S, Anerillas C, Martindale J, Belair C, Munk R, et al.
bioRxiv
. 2023 Aug;
PMID: 37609272
Senescence is a state of indefinite cell cycle arrest associated with aging, cancer, and age-related diseases. Here, using label-based mass spectrometry, ribosome profiling and nanopore direct RNA sequencing, we explore...