Dimitrios Tsitsipatis
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Explore the profile of Dimitrios Tsitsipatis including associated specialties, affiliations and a list of published articles.
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40
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604
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Recent Articles
1.
Lodde V, Zarbo I, Farina G, Masia A, Solla P, Campesi I, et al.
Cells
. 2024 Oct;
13(19.
PMID: 39404430
Multiple sclerosis (MS) is a demyelinating autoimmune disease characterized by early onset, for which the interaction of genetic and environmental factors is crucial. Dysregulation of the immune system as well...
2.
Olinger B, Banarjee R, Dey A, Tsitsipatis D, Tanaka T, Ram A, et al.
medRxiv
. 2024 Oct;
PMID: 39371126
Cellular senescence increases with age and contributes to age-related declines and pathologies. We identified circulating biomarkers of senescence associated with diverse clinical traits in humans to facilitate future non-invasive assessment...
3.
Abdelmohsen K, Mazan-Mamczarz K, Munk R, Tsitsipatis D, Meng Q, Rossi M, et al.
Aging Cell
. 2024 Aug;
23(11):e14297.
PMID: 39143693
Cellular senescence, a state of persistent growth arrest, is closely associated with aging and age-related diseases. Deciphering the heterogeneity within senescent cell populations and identifying therapeutic targets are paramount for...
4.
Ji E, Pandey P, Martindale J, Yang X, Yang J, Tsitsipatis D, et al.
Mol Cell Biol
. 2024 Aug;
44(9):391-409.
PMID: 39133076
Myogenesis is a highly orchestrated process whereby muscle precursor cells, myoblasts, develop into muscle fibers to form skeletal muscle during embryogenesis and regenerate adult muscle. Here, we studied the RNA-binding...
5.
Shin C, Rossi M, Anerillas C, Martindale J, Yang X, Ji E, et al.
Mol Cell Biol
. 2024 May;
44(5):194-208.
PMID: 38769646
Cellular senescence is a dynamic biological process triggered by sublethal cell damage and driven by specific changes in gene expression programs. We recently identified ANKRD1 (ankyrin repeat domain 1) as...
6.
Rossi M, Banskota N, Shin C, Anerillas C, Tsitsipatis D, Yang J, et al.
Nucleic Acids Res
. 2024 May;
52(12):7261-7278.
PMID: 38721764
RNA modifications, including N6-methyladenosine (m6A), critically modulate protein expression programs in a range of cellular processes. Although the transcriptomes of cells undergoing senescence are strongly regulated, the landscape and impact...
7.
Zonnefeld A, Cui C, Tsitsipatis D, Piao Y, Fan J, Mazan-Mamczarz K, et al.
Aging (Albany NY)
. 2024 Apr;
16(8):6717-6730.
PMID: 38637019
Evaporation of sweat on the skin surface is the major mechanism for dissipating heat in humans. The secretory capacity of sweat glands (SWGs) declines during aging, leading to heat intolerance...
8.
Yang J, Tsitsipatis D, Gorospe M
Wiley Interdiscip Rev RNA
. 2024 Apr;
15(2):e1841.
PMID: 38576135
Long noncoding (lnc)RNAs modulate gene expression programs in a range of developmental processes in different organs. In skeletal muscle, lncRNAs have been implicated in myogenesis, the process whereby muscle precursor...
9.
Abdelmohsen K, Herman A, Carr A, Henry-Smith C, Rossi M, Meng Q, et al.
J Extracell Biol
. 2023 Sep;
2(8).
PMID: 37744304
Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of...
10.
Anerillas C, Mazan-Mamczarz K, Herman A, Munk R, Lam K, Calvo-Rubio M, et al.
Nat Aging
. 2023 Sep;
3(10):1237-1250.
PMID: 37667102
Sublethal cell damage can trigger senescence, a complex adaptive program characterized by growth arrest, resistance to apoptosis and a senescence-associated secretory phenotype (SASP). Here, a whole-genome CRISPR knockout screen revealed...