Carlo R Largiader
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Explore the profile of Carlo R Largiader including associated specialties, affiliations and a list of published articles.
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74
Citations
1102
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Recent Articles
1.
Bastian S, Joerger M, Holer L, Bartschi D, Guckenberger M, Jochum W, et al.
Clin Colorectal Cancer
. 2024 Nov;
24(1):82-88.e1.
PMID: 39537446
Background: The multi tyrosine kinase inhibitor regorafenib is active in metastatic colorectal cancer. Improvement in clinical outcome by adding regorafenib to long-course chemoradiotherapy (LcCRT) was investigated in molecularly undefined LARC....
2.
Heini A, Kammermann K, Bacher U, Jeker B, Hayoz M, Aebi Y, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39409984
Introduction: The growing body of evidence around sexual and gender dimorphism in medicine, particularly in oncology, has highlighted differences in treatment response, outcomes, and side effects between males and females....
3.
Prost J, Brunner F, Bovet C, Grob C, Berchtold C, Schlotterbeck G, et al.
Clin Mass Spectrom
. 2024 Aug;
3:1-6.
PMID: 39193097
Bile acids malabsorption (BAM) is encountered in numerous gastrointestinal pathologies and is a good example of a treatable cause of watery diarrhea after ileal resection. The gold standard for diagnosing...
4.
Aycicek S, Akhoundova D, Bacher U, Hayoz M, Aebi Y, Largiader C, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125785
Limited data on treosulfan pharmacokinetics in adults, particularly regarding autologous stem cell transplantation (ASCT) in acute myeloid leukemia (AML), is available to date. Furthermore, correlations between treosulfan exposure, toxicity, and...
5.
Ambrodji A, Sadlon A, Amstutz U, Hoch D, Berger M, Bastian S, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39062841
Pre-treatment genotyping of four well-characterized toxicity risk-variants in the dihydropyrimidine dehydrogenase gene () has been widely implemented in Europe to prevent serious adverse effects in cancer patients treated with fluoropyrimidines....
6.
Nagler M, Nilius H, Michielin G, Masoodi M, Largiader C
Pol Arch Intern Med
. 2024 Jun;
134(7-8).
PMID: 38884596
Laboratory tests play a central role in medicine, as they help to make diagnoses, assess prognosis and risk of disease, and monitor therapies, thus contributing to 70% of all medical...
7.
Eggimann M, Akhoundova D, Nilius H, Hoffmann M, Hayoz M, Aebi Y, et al.
Cancers (Basel)
. 2024 May;
16(10).
PMID: 38791965
(1) Background: Treosulfan and melphalan (TreoMel)-based high-dose chemotherapy (HDCT) has shown promising safety and efficacy as a conditioning regimen for acute myeloid leukemia (AML) patients undergoing autologous stem cell transplantation...
8.
Morandi S, Herzog E, Munk M, Kreuzer M, Largiader C, Wolf S, et al.
J Neuroinflammation
. 2024 May;
21(1):120.
PMID: 38715051
Background: The human gut microbiome (GM) is involved in inflammation and immune response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic invasion, disrupts immune equilibrium, and potentially triggers diseases...
9.
Zhang T, Ambrodji A, Huang H, Bouchonville K, Etheridge A, Schmidt R, et al.
Elife
. 2024 Apr;
13.
PMID: 38686795
Enhancers are critical for regulating tissue-specific gene expression, and genetic variants within enhancer regions have been suggested to contribute to various cancer-related processes, including therapeutic resistance. However, the precise mechanisms...
10.
Neyer P, Kabore B, Nakas C, Diallo S, Tinto H, Post A, et al.
Br J Haematol
. 2024 Jan;
204(5):2066-2070.
PMID: 38279554
We assessed the diagnostic potential of erythroferrone as a biomarker for iron homeostasis comparing iron deficiency cases with anaemia of inflammation and controls. The dysregulation of the hepcidin axis was...