Carlo R Largiader
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Explore the profile of Carlo R Largiader including associated specialties, affiliations and a list of published articles.
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74
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1102
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Recent Articles
11.
Le Teuff G, Cozic N, Boyer J, Boige V, Diasio R, Taieb J, et al.
Br J Cancer
. 2024 Jan;
130(5):808-818.
PMID: 38225422
Background: Dihydropyrimidine dehydrogenase (DPD) deficiency is the main known cause of life-threatening fluoropyrimidine (FP)-induced toxicities. We conducted a meta-analysis on individual patient data to assess the contribution of deleterious DPYD...
12.
Zhang T, Ambrodji A, Huang H, Bouchonville K, Etheridge A, Schmidt R, et al.
bioRxiv
. 2023 Nov;
PMID: 37961517
Enhancers are critical for regulating tissue-specific gene expression, and genetic variants within enhancer regions have been suggested to contribute to various cancer-related processes, including therapeutic resistance. However, the precise mechanisms...
13.
Neyer P, Kabore B, Nakas C, Hartmann B, Post A, Diallo S, et al.
Malar J
. 2023 Sep;
22(1):252.
PMID: 37658365
Background: Asymptomatic Plasmodium falciparum parasitaemia forms a reservoir for the transmission of malaria disease in West Africa. Certain haemoglobin variants are known to protect against severe malaria infection. However, data...
14.
Kueng N, Sidler D, Banz V, Largiader C, Ng C, Amstutz U
Diagnostics (Basel)
. 2023 Aug;
13(15).
PMID: 37568867
Methylation sequencing is a promising approach to infer the tissue of origin of cell-free DNA (cfDNA). In this study, a single- and a double-stranded library preparation approach were evaluated with...
15.
Gillich C, Akhoundova D, Hayoz M, Aebi Y, Largiader C, Seipel K, et al.
Cancers (Basel)
. 2023 Jun;
15(10).
PMID: 37345036
(1) Background: Upfront treatment consolidation with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) has relevantly contributed to achieving durable remissions following induction treatment in multiple myeloma (MM) patients....
16.
Kueng N, Arcioni S, Sandberg F, Kuhn C, Banz V, Largiader C, et al.
Front Genet
. 2023 Feb;
14:1089830.
PMID: 36777723
In allograft monitoring of solid organ transplant recipients, liquid biopsy has emerged as a novel approach using quantification of donor-derived cell-free DNA (dd-cfDNA) in plasma. Despite early clinical implementation and...
17.
Schmulenson E, Bovet C, Theurillat R, Decosterd L, Largiader C, Prost J, et al.
Br J Clin Pharmacol
. 2022 Jul;
88(12):5336-5347.
PMID: 35831229
Aims: Locally advanced rectal cancer (LARC) is an area of unmet medical need with one third of patients dying from their disease. With response to neoadjuvant chemo-radiotherapy being a major...
18.
Begre U, Jorger M, Aebi S, Amstutz U, Largiader C
Front Pharmacol
. 2022 Jun;
13:885259.
PMID: 35662713
The implementation of pharmacogenetic testing into clinical practice has been a slow process so far. Here, we review the implementation of pre-treatment testing of dihydropyrimidine dehydrogenase gene () risk variants...
19.
Gurevich E, Hayoz M, Aebi Y, Largiader C, Taleghani B, Bacher U, et al.
Cancers (Basel)
. 2022 Feb;
14(4).
PMID: 35205772
(1) Background: High-dose chemotherapy (HDCT) before autologous stem cell transplantation (ASCT) in acute myeloid leukemia (AML) patients predominantly combines busulfan with cyclophosphamide or melphalan. Treosulfan compares favorably regarding lower inter-individual...
20.
Horn M, Jonsdottir H, Brigger D, Damonti L, Suter-Riniker F, Endrich O, et al.
Allergy
. 2022 Jan;
77(7):2090-2103.
PMID: 34986501
Background: Serological tests are a powerful tool in the monitoring of infectious diseases and the detection of host immunity. However, manufacturers often provide diagnostic accuracy data generated through biased studies,...