Carles Solsona
Overview
Explore the profile of Carles Solsona including associated specialties, affiliations and a list of published articles.
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29
Citations
701
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Recent Articles
1.
Cases M, Dorca-Arevalo J, Blanch M, Rodil S, Terni B, Martin-Satue M, et al.
Pharmacol Res Perspect
. 2024 Sep;
12(5):e70005.
PMID: 39320019
The epsilon toxin (Etx) from Clostridium perfringens has been identified as a potential trigger of multiple sclerosis, functioning as a pore-forming toxin that selectively targets cells expressing the plasma membrane...
2.
Blanch M, Dorca-Arevalo J, Not A, Cases M, Gomez de Aranda I, Martinez-Yelamos A, et al.
Mol Cell Biol
. 2018 Jul;
38(19).
PMID: 29987189
Epsilon toxin (Etx) from is a pore-forming protein that crosses the blood-brain barrier, binds to myelin, and, hence, has been suggested to be a putative agent for the onset of...
3.
Wang Y, Rico-Lastres P, Lezamiz A, Mora M, Solsona C, Stirnemann G, et al.
J Phys Chem Lett
. 2018 Jun;
9(14):3800-3807.
PMID: 29924934
Understanding the molecular mechanisms governing protein-nucleic acid interactions is fundamental to many nuclear processes. However, how nucleic acid binding affects the conformation and dynamics of the substrate protein remains poorly...
4.
Cases M, Llobet A, Terni B, Gomez de Aranda I, Blanch M, Doohan B, et al.
eNeuro
. 2017 Aug;
4(4).
PMID: 28798954
ε-Toxin is a pore forming toxin produced by types B and D. It is synthesized as a less active prototoxin form that becomes fully active upon proteolytic activation. The toxin...
5.
Gaitan-Penas H, Gradogna A, Laparra-Cuervo L, Solsona C, Fernandez-Duenas V, Barrallo-Gimeno A, et al.
Biophys J
. 2016 Oct;
111(7):1429-1443.
PMID: 27705766
Volume-regulated anion channels (VRACs) play an important role in controlling cell volume by opening upon cell swelling. Recent work has shown that heteromers of LRRC8A with other LRRC8 members (B,...
6.
Alvarez-Zaldiernas C, Lu J, Zheng Y, Yang H, Blasi J, Solsona C, et al.
J Biol Chem
. 2016 Jun;
291(33):17197-208.
PMID: 27261461
Protein misfolding is implicated in neurodegenerative diseases such as ALS, where mutations of superoxide dismutase 1 (SOD1) account for about 20% of the inherited mutations. Human SOD1 (hSOD1) contains four...
7.
Rodrigues R, Almeida T, Diaz-Hernandez M, Marques J, Franco R, Solsona C, et al.
Neuropharmacology
. 2016 Jan;
105:241-257.
PMID: 26801076
Previous studies documented a cross-talk between purinergic P2X (P2XR) and nicotinic acetylcholine receptors (nAChR) in heterologous expression systems and peripheral preparations. We now investigated if this occurred in native brain...
8.
Solsona C, Kahn T, Badilla C, Alvarez-Zaldiernas C, Blasi J, Fernandez J, et al.
J Biol Chem
. 2014 Aug;
289(39):26722-26732.
PMID: 25096579
Neurodegenerative diseases share a common characteristic, the presence of intracellular or extracellular deposits of protein aggregates in nervous tissues. Amyotrophic Lateral Sclerosis (ALS) is a severe and fatal neurodegenerative disorder,...
9.
Pizarro-Delgado J, Fasciani I, Temperan A, Romero M, Gonzalez-Nieto D, Alonso-Magdalena P, et al.
Am J Physiol Endocrinol Metab
. 2014 Apr;
306(12):E1354-66.
PMID: 24735890
The existence of functional connexin36 (Cx36) hemichannels in β-cells was investigated in pancreatic islets of rat and wild-type (Cx36(+/+)), monoallelic (Cx36(+/-)), and biallelic (Cx36(-/-)) knockout mice. Hemichannel opening by KCl...
10.
Nualart-Marti A, del Molino E, Grandes X, Bahima L, Martin-Satue M, Puchal R, et al.
Glia
. 2013 Oct;
61(12):1976-89.
PMID: 24123415
Extracellular purines elicit strong signals in the nervous system. Adenosine-5'-triphosphate (ATP) does not spontaneously cross the plasma membrane, and nervous cells secrete ATP by exocytosis or through plasma membrane proteins...