Carla N Castro
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Explore the profile of Carla N Castro including associated specialties, affiliations and a list of published articles.
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11
Citations
600
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Recent Articles
1.
Almeida L, Dhillon-LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, et al.
Immunity
. 2020 Nov;
54(1):68-83.e6.
PMID: 33238133
While antibiotics are intended to specifically target bacteria, most are known to affect host cell physiology. In addition, some antibiotic classes are reported as immunosuppressive for reasons that remain unclear....
2.
Maccari M, Fuchs S, Kury P, Andrieux G, Volkl S, Bengsch B, et al.
J Exp Med
. 2020 Nov;
218(2).
PMID: 33170215
The identification and characterization of rare immune cell populations in humans can be facilitated by their growth advantage in the context of specific genetic diseases. Here, we use autoimmune lymphoproliferative...
3.
Ammann S, Fuchs S, Martin-Martin L, Castro C, Spielberger B, Klemann C, et al.
J Allergy Clin Immunol
. 2019 Sep;
145(1):434-437.e4.
PMID: 31526803
No abstract available.
4.
Maccari M, Speckmann C, Heeg M, Reimer A, Casetti F, Has C, et al.
Clin Immunol
. 2019 Jun;
208:108228.
PMID: 31195081
This study reports a patient with severe skin disease in the context of profound immunodeficiency explained by two concomitant genetic diseases caused by two novel homozygous loss-of-function mutations in PLEC1...
5.
Andreas N, Riemann M, Castro C, Groth M, Koliesnik I, Engelmann C, et al.
Eur J Immunol
. 2018 Feb;
48(6):923-936.
PMID: 29485182
The NF-κB transcription factor subunit RelB is important for the full activation of conventional dendritic cells (cDCs) during T-cell-dependent immune responses. Although the number of splenic DCs is greatly reduced...
6.
Barcala Tabarrozzi A, Andreone L, Deckers J, Castro C, Gimeno M, Ariolfo L, et al.
Sci Rep
. 2016 Nov;
6:36646.
PMID: 27857212
Dendritic cells (DC) initiate the adaptive immune response. Glucocorticoids (GCs) down-modulate the function of DC. Compound A (CpdA, (2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride) is a plant-derived GR-ligand with marked dissociative properties. We investigated...
7.
Raha S, Raud B, Oberdorfer L, Castro C, Schreder A, Freitag J, et al.
Eur J Immunol
. 2016 Jun;
46(9):2233-8.
PMID: 27338930
Upon antigen-specific or allogeneic activation, T cells sharply increase their metabolic activity to cope with augmented needs for proliferation and effector functions. Therefore, enzymes involved in energy metabolism constitute attractive...
8.
Berod L, Friedrich C, Nandan A, Freitag J, Hagemann S, Harmrolfs K, et al.
Nat Med
. 2015 Apr;
21(4):414.
PMID: 25849276
No abstract available.
9.
Berod L, Friedrich C, Nandan A, Freitag J, Hagemann S, Harmrolfs K, et al.
Nat Med
. 2014 Oct;
20(11):1327-33.
PMID: 25282359
Interleukin-17 (IL-17)-secreting T cells of the T helper 17 (TH17) lineage play a pathogenic role in multiple inflammatory and autoimmune conditions and thus represent a highly attractive target for therapeutic...
10.
Liberman A, Antunica-Noguerol M, Ferraz-de-Paula V, Palermo-Neto J, Castro C, Druker J, et al.
PLoS One
. 2012 Apr;
7(4):e35155.
PMID: 22496903
Background: Compound A (CpdA) is a dissociating non-steroidal glucocorticoid receptor (GR) ligand which has anti-inflammatory properties exerted by down-modulating proinflammatory gene expression. By favouring GR monomer formation, CpdA does not...