Carl J Johnston
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Explore the profile of Carl J Johnston including associated specialties, affiliations and a list of published articles.
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55
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917
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Recent Articles
1.
Strohm A, Oldfield S, Hernady E, Johnston C, Marples B, OBanion M, et al.
Brain Behav Immun Health
. 2024 Dec;
43():100911.
PMID: 39677060
Patients receiving cranial radiation therapy experience tissue damage and cognitive deficits that severely decrease their quality of life. Experiments in rodent models show that these adverse neurological effects are in...
2.
Hughson A, Hannon G, Salama N, Vrooman T, Stockwell C, Mills B, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(4):102350.
PMID: 39469666
Pronounced T cell exhaustion characterizes immunosuppressive tumors, with the tumor microenvironment (TME) employing multiple mechanisms to elicit this suppression. Traditional immunotherapies, such as immune checkpoint blockade, often fail due to...
3.
Croft D, Utell M, Hopke P, Liu H, Lin S, Thurston S, et al.
J Expo Sci Environ Epidemiol
. 2024 Aug;
PMID: 39127830
Background: Influenza healthcare encounters in adults associated with specific sources of PM is an area of active research. Objective: Following 2017 legislation requiring reductions in emissions from light-duty vehicles, we...
4.
Groves A, Paris N, Johnston C, Hernady E, Finkelstein J, Lawrence P, et al.
Radiat Res
. 2024 Jul;
202(3):552-564.
PMID: 39048109
Inflammation is a key factor in both influenza and radiation-induced lung pathophysiology. This implies a commonality of response to pulmonary damage from these insults and suggests exacerbated pathology may occur...
5.
Hughson A, Hannon G, Salama N, Vrooman T, Stockwell C, Mills B, et al.
bioRxiv
. 2023 Nov;
PMID: 37961513
Statement Of Significance: This study demonstrates the use of a novel combination treatment consisting of radiation and immunotherapy in murine pancreatic tumors. This treatment could effectively treat local and metastatic...
6.
House E, Kim S, Chalupa D, Hernady E, Groves A, Johnston C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Aug;
325(4):L434-L446.
PMID: 37642674
Bronchiolitis obliterans (BO) is a devastating lung disease that can develop following inhalation exposure to certain chemicals. Diacetyl (DA) is one chemical commonly associated with BO development when inhaled at...
7.
Ye J, Gavras N, Keeley D, Hughson A, Hannon G, Vrooman T, et al.
J Immunother Cancer
. 2023 May;
11(5).
PMID: 37142292
Background: Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of...
8.
Day N, Wang J, Johnston C, Kim S, Olson H, House E, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Mar;
324(5):L571-L583.
PMID: 36881561
E-cigarette liquids are complex mixtures of chemicals consisting of humectants, such as propylene glycol (PG) and vegetable glycerin (VG), with nicotine or flavorings added. Published literature emphasizes the toxicity of...
9.
Groves A, Misra R, Clair G, Hernady E, Olson H, Orton D, et al.
Radiother Oncol
. 2023 Feb;
183:109543.
PMID: 36813173
Background: The lung is sensitive to radiation, increasing normal tissue toxicity risks following radiation therapy. Adverse outcomes include pneumonitis and pulmonary fibrosis, which result from dysregulated intercellular communication within the...
10.
Groves A, Johnston C, Beutner G, Dahlstrom J, Koina M, OReilly M, et al.
Physiol Rep
. 2022 Dec;
10(24):e15533.
PMID: 36541220
Hypoxic ischemic encephalopathy (HIE) is associated with acute kidney injury (AKI) in neonates with birth asphyxia. This study aimed to utilize urinary biomarkers to characterize AKI in an established neonatal...