Carl F Schaefer
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Explore the profile of Carl F Schaefer including associated specialties, affiliations and a list of published articles.
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20
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2298
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Recent Articles
1.
Efroni S, Meerzaman D, Schaefer C, Greenblum S, Soo-Lyu M, Hu Y, et al.
IET Syst Biol
. 2014 Apr;
7(6):243-51.
PMID: 24712101
The development and progression of cancer is associated with disruption of biological networks. Historically studies have identified sets of signature genes involved in events ultimately leading to the development of...
2.
Meerzaman D, Yan C, Chen Q, Edmonson M, Schaefer C, Clifford R, et al.
Cancer Genomics Proteomics
. 2014 Mar;
11(1):1-12.
PMID: 24633315
We report on next-generation transcriptome sequencing results of three human hepatocellular carcinoma tumor/tumor-adjacent pairs. This analysis robustly examined ∼12,000 genes for both expression differences and molecular alterations. We observed 4,513...
3.
Greenblum S, Efroni S, Schaefer C, Buetow K
BMC Bioinformatics
. 2011 May;
12:133.
PMID: 21542931
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provide a robust alternative...
4.
Efroni S, Ben-Hamo R, Edmonson M, Greenblum S, Schaefer C, Buetow K
PLoS One
. 2011 Feb;
6(1):e14437.
PMID: 21283511
High resolution, system-wide characterizations have demonstrated the capacity to identify genomic regions that undergo genomic aberrations. Such research efforts often aim at associating these regions with disease etiology and outcome....
5.
Temple G, Gerhard D, Rasooly R, Feingold E, Good P, Robinson C, et al.
Genome Res
. 2009 Sep;
19(12):2324-33.
PMID: 19767417
Since its start, the Mammalian Gene Collection (MGC) has sought to provide at least one full-protein-coding sequence cDNA clone for every human and mouse gene with a RefSeq transcript, and...
6.
Duncan C, Leary R, Cheng-Ho Lin J, Cummins J, Di C, Schaefer C, et al.
BMC Med Genomics
. 2009 May;
2:22.
PMID: 19426505
Background: Microorganisms have been associated with many types of human diseases; however, a significant number of clinically important microbial pathogens remain to be discovered. Methods: We have developed a genome-wide...
7.
Schaefer C, Anthony K, Krupa S, Buchoff J, Day M, Hannay T, et al.
Nucleic Acids Res
. 2008 Oct;
37(Database issue):D674-9.
PMID: 18832364
The Pathway Interaction Database (PID, http://pid.nci.nih.gov) is a freely available collection of curated and peer-reviewed pathways composed of human molecular signaling and regulatory events and key cellular processes. Created in...
8.
Efroni S, Schaefer C, Buetow K
PLoS One
. 2007 May;
2(5):e425.
PMID: 17487280
Cancer is recognized to be a family of gene-based diseases whose causes are to be found in disruptions of basic biologic processes. An increasingly deep catalogue of canonical networks details...
9.
Riss J, Khanna C, Koo S, Chandramouli G, Yang H, Hu Y, et al.
Cancer Res
. 2006 Jul;
66(14):7216-24.
PMID: 16849569
Cancers have been described as wounds that do not heal, suggesting that the two share common features. By comparing microarray data from a model of renal regeneration and repair (RRR)...
10.
Gerhard D, Wagner L, Feingold E, Shenmen C, Grouse L, Schuler G, et al.
Genome Res
. 2004 Oct;
14(10B):2121-7.
PMID: 15489334
The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every...