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Carl Christoph Goetzke

Explore the profile of Carl Christoph Goetzke including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 188
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Recent Articles
1.
Goetzke C, Massoud M, Frischbutter S, Guerra G, Ferreira-Gomes M, Heinrich F, et al.
Nature . 2025 Mar; PMID: 40074901
In a subset of children and adolescents, SARS-CoV-2 infection induces a severe acute hyperinflammatory shock termed multisystem inflammatory syndrome in children (MIS-C) at four to eight weeks after infection. MIS-C...
2.
Bjelde A, Leitz D, Goetzke C, von Stuckrad A, Thumfart J, Kallinich T
Klin Padiatr . 2025 Feb; 237(2):102-105. PMID: 39900083
No abstract available.
3.
Budzinski L, Sempert T, Lietz L, Maier R, Kang G, von Stuckrad A, et al.
Mol Cell Pediatr . 2024 Dec; 11(1):12. PMID: 39653980
Objective: Juvenile Idiopathic Arthritis (JIA) comprises diverse chronic inflammatory conditions driven by malfunction of the immune system. The intestinal microbiota is considered a crucial environmental factor correlating with chronic inflammatory...
4.
Kespohl M, Goetzke C, Althof N, Bredow C, Kelm N, Pinkert S, et al.
Arterioscler Thromb Vasc Biol . 2024 Feb; 44(4):843-865. PMID: 38385286
Background: Accumulating evidence implicates the activation of G-protein-coupled PARs (protease-activated receptors) by coagulation proteases in the regulation of innate immune responses. Methods: Using mouse models with genetic alterations of the...
5.
Wolf C, Lim E, Mokhtari M, Kind B, Odainic A, Lara-Villacanas E, et al.
Sci Immunol . 2024 Jan; 9(92):eadi9769. PMID: 38207055
UNC93B1 is critical for trafficking and function of nucleic acid-sensing Toll-like receptors (TLRs) TLR3, TLR7, TLR8, and TLR9, which are essential for antiviral immunity. Overactive TLR7 signaling induced by recognition...
6.
Knieper A, von Stuckrad A, Minden K, Goetzke C, Kallinich T
Z Rheumatol . 2023 Nov; 83(1):4-14. PMID: 37921883
Monogenic mutations in laccase domain-containing 1 (LACC1) are associated with clinical pictures that mimic severe courses of polyarticular or systemic juvenile idiopathic arthritis. The diseases are characterized by an early...
7.
Goetzke C, Ebstein F, Kallinich T
J Clin Med . 2021 Apr; 10(8). PMID: 33923887
The ubiquitin-proteasome system (UPS) is involved in multiple cellular functions including the regulation of protein homeostasis, major histocompatibility (MHC) class I antigen processing, cell cycle proliferation and signaling. In humans,...
8.
Tomaras S, Goetzke C, Kallinich T, Feist E
J Clin Med . 2021 Mar; 10(4). PMID: 33673234
Adult-onset Still's disease (AoSD) is a rare systemic autoinflammatory disease characterized by arthritis, spiking fever, skin rash and elevated ferritin levels. The reason behind the nomenclature of this condition is...
9.
Goetzke C, Althof N, Neumaier H, Heuser A, Kaya Z, Kespohl M, et al.
Basic Res Cardiol . 2021 Feb; 116(1):7. PMID: 33523326
A preclinical model of troponin I-induced myocarditis (AM) revealed a prominent role of the immunoproteasome (ip), the main immune cell-resident proteasome isoform, in heart-directed autoimmunity. Viral infection of the heart...
10.
Orak B, Ngoumou G, Ebstein F, Zieba B, Goetzke C, Knierim E, et al.
Pediatr Allergy Immunol . 2020 Oct; 32(3):621-625. PMID: 33099809
No abstract available.