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Karin Klingel

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Articles 392
Citations 12747
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Recent Articles
1.
Halushka M, dAmati G, Bois M, De Gaspari M, Giordano C, Klingel K, et al.
Cardiovasc Pathol . 2025 Mar; :107733. PMID: 40089045
Lymphocytic myocarditis is a serious disease with significant morbidity and mortality. Cardiovascular pathology has an important role in its diagnosis, a diagnosis historically made using the presence of a lymphocytic...
2.
Kelm N, Kespohl M, Smagurauskaite G, Vales S, Karuppanan K, Mburu P, et al.
Basic Res Cardiol . 2025 Feb; PMID: 40009121
Myocarditis, an inflammatory disease of the heart muscle, is often triggered by viral infections. This inflammation, which can lead to severe cardiac dysfunction and adverse outcomes, is mediated by various...
3.
Maatz H, Lindberg E, Adami E, Lopez-Anguita N, Perdomo-Sabogal A, Cocera Ortega L, et al.
Nat Cardiovasc Res . 2025 Feb; PMID: 39994453
Myocarditis, characterized by inflammatory cell infiltration, can have multiple etiologies, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or, rarely, mRNA-based coronavirus disease 2019 (COVID-19) vaccination. The underlying cellular...
4.
Hamidi J, Hanel Y, Dittmann S, Gerding W, Nguyen H, Klingel K, et al.
Front Cardiovasc Med . 2025 Feb; 12:1462523. PMID: 39963604
Background: Hypertrophic cardiomyopathy (HCM) is characterized by an increased left ventricular (LV) wall thickness and LV mass. With an estimated prevalence of 1:200-500, HCM is among the most common genetically...
5.
Cameli M, Pieroni M, Pastore M, Brucato A, Castelletti S, Crotti L, et al.
Eur Heart J Cardiovasc Imaging . 2025 Feb; PMID: 39903606
Anderson-Fabry disease (AFD) is a rare genetic disease with X-linked transmission characterized by a defect in the enzyme alpha-galactosidase A (alpha-GAL), which impairs glycosphingolipid metabolism and leads to an excessive...
6.
Holtzhausen C, Heil L, Klingel K, Fox H, Gummert J, Gartner A, et al.
Hum Mol Genet . 2025 Feb; PMID: 39895064
Mutations in the human FLNC gene encoding filamin C (FLNc) cause a broad spectrum of sporadic and familial cardiomyopathies and myopathies. We report on the genetic, clinical, morphological and biochemical...
7.
Lerchner T, Mincu R, Buhning F, Vogel J, Klingel K, Meetschen M, et al.
Int J Cardiol Heart Vasc . 2025 Jan; 56:101581. PMID: 39882168
Background And Aims: Cardiotoxicity from immune checkpoint inhibitor (ICI) therapy is a challenge in clinical practice, and the assessment of ICI-related myocarditis (ICI-M) is often complicated by a variable phenotype....
8.
Muller M, Brand A, Mattig I, Spethmann S, Messroghli D, Hahn K, et al.
Circ Heart Fail . 2025 Jan; 18(2):e012146. PMID: 39866106
Background: Despite previous histopathologic evidence for its presence, the role of myocardial inflammation in the development and progression of cardiac transthyretin amyloidosis (ATTR-CA) remains insufficiently understood. Thus, this study sought...
9.
Raj Murthi S, Petry A, Shashikadze B, Stockl J, Schmid M, Santamaria G, et al.
Sci Rep . 2025 Jan; 15(1):2132. PMID: 39820339
Hypertrophic cardiomyopathy (HCM) caused by autosomal-dominant mutations in genes coding for structural sarcomeric proteins, is the most common inherited heart disease. HCM is associated with myocardial hypertrophy, fibrosis and ventricular...
10.
Seuthe K, Pfister R, Pennig L, Mons U, Klingel K, Freyhaus H
Clin Res Cardiol . 2024 Nov; PMID: 39570399
Background: In the past decades, cardiovascular magnetic resonance (CMR) was established as a non-invasive tool supporting the diagnosis of myocarditis and there is often reluctance in performing EMB due to...