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Carl A Hubel

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Recent Articles
1.
Wang T, Bryan S, Jeyabalan A, Facco F, Gandley R, Hubel C, et al.
Am J Perinatol . 2024 Feb; 41(9):1113-1119. PMID: 38373709
Objective: This study aimed to compare sleep quality at 1 year postpartum following a hypertensive disorder of pregnancy (HDP) among individuals with persistent postpartum hypertension (HTN) compared with those with...
2.
Jancsura M, Schmella M, Helsabeck N, Gillespie S, Roberts J, Conley Y, et al.
Am J Reprod Immunol . 2023 Aug; 90(3):e13763. PMID: 37641371
Problem: Obesity and preeclampsia both involve a pathological inflammatory response, which may be how obesity increases preeclampsia risk. Previous studies have failed to assess robust measurements of inflammatory markers across...
3.
Liu S, Fu H, Ray M, Heinsberg L, Conley Y, Anderson C, et al.
Epigenetics Commun . 2023 Apr; 3(1). PMID: 37063698
Background: While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that may...
4.
Powell J, Gandley R, Lackner E, Dolinish A, Ouyang Y, Powers R, et al.
Pregnancy Hypertens . 2022 Mar; 28:66-73. PMID: 35240546
Preeclampsia (PE) is a common syndrome of pregnancy, characterized by new-onset hypertension and proteinuria after gestational week 20, or new onset of hypertension and significant end-organ dysfunction. In the worst...
5.
Catov J, Muldoon M, Gandley R, Brands J, Hauspurg A, Hubel C, et al.
Hypertension . 2021 Dec; 79(2):424-434. PMID: 34879703
Women with adverse pregnancy outcomes later experience excess hypertension and cardiovascular disease, but how the events are linked is unknown. Examination of the placenta may provide clues to vascular impairments...
6.
Ray M, Heinsberg L, Conley Y, Roberts J, Jeyabalan A, Hubel C, et al.
Hypertens Pregnancy . 2021 Oct; 40(4):312-321. PMID: 34697971
Examine white blood cell (WBC) proportions across preeclamptic (n = 28 cases) and normotensive (n = 28 controls) pregnancy in individuals with overweight/obesity. WBC proportions were inferred from genome-wide DNA...
7.
Heinsberg L, Ray M, Conley Y, Roberts J, Jeyabalan A, Hubel C, et al.
Reprod Sci . 2021 Apr; 28(12):3519-3528. PMID: 33877642
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality. Chronological age and race are associated with preeclampsia, but the role of these factors is not entirely understood....
8.
St-Onge M, Aggarwal B, Allison M, Berger J, Castaneda S, Catov J, et al.
J Am Heart Assoc . 2021 Feb; 10(5):e019519. PMID: 33619972
The Go Red for Women movement was initiated by the American Heart Association (AHA) in the early 2000s to raise awareness concerning cardiovascular disease (CVD) risk in women. In 2016,...
9.
Rietze A, Conley Y, Ren D, Anderson C, Roberts J, Jeyabalan A, et al.
Epigenet Insights . 2020 Oct; 13:2516865720959682. PMID: 33103056
Objective: We compared blood-based DNA methylation levels of endoglin () and transforming growth factor beta receptor 2 () gene promoter regions between women with clinically-overt preeclampsia and women with uncomplicated,...
10.
Sun B, Bertolet M, Brooks M, Hubel C, Lewis C, Gunderson E, et al.
J Am Heart Assoc . 2020 Jul; 9(15):e015900. PMID: 32696706
Background Women who deliver preterm infants (<37 weeks) have excess cardiovascular risk; however, it is unclear whether the unfavorable changes in the cardiometabolic profile associated with preterm delivery initiate before,...