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Cao Chen

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Articles 178
Citations 1743
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Recent Articles
11.
Feng Y, Zhao X, Chen Z, Wu Y, Li L, Wu C, et al.
J Med Virol . 2024 May; 96(5):e29664. PMID: 38727137
The causative agent of coronavirus disease 2019 (COVID-19), known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread accumulatively to 240 countries and continues to evolve. To gain a...
12.
Zhou D, Jia X, Wu Y, Zhang W, Wang Y, Liang D, et al.
Mol Neurobiol . 2024 Apr; 61(11):9582-9594. PMID: 38664301
Neuroinflammation is a common pathological feature in a number of neurodegenerative diseases, which is mediated primarily by the activated glial cells. Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing-3 (NLRP3) inflammasome-associated neuroinflammatory...
13.
Jia X, Hu C, Chen C, Gao L, Liang D, Zhou W, et al.
Front Mol Neurosci . 2024 Feb; 17:1341886. PMID: 38390431
Background And Purpose: Calmodulin (CaM) levels exhibit significant elevation in the brain tissue of rodent and cell line models infected with prion, as well as in the cerebrospinal fluid (CSF)...
14.
Yao C, Sun J, Luo W, Chen H, Chen T, Chen C, et al.
Bone Joint Res . 2024 Jan; 13(2):52-65. PMID: 38295830
Aims: To investigate the effects of senescent osteocytes on bone homeostasis in the progress of age-related osteoporosis and explore the underlying mechanism. Methods: In a series of in vitro experiments,...
15.
Wang Y, Sun X, Chen C, Ge H, Sun J, Li E, et al.
Cancer Lett . 2024 Jan; 585:216654. PMID: 38272344
Tumor micronecrosis is a pathological feature that reflects malignant biological behavior in hepatocellular carcinoma (HCC). However, whether micronecrosis can optimize HCC staging systems remains unilluminated. A total of 1632 HCC...
16.
Chen C, Zhang Y, Chen H, Sun J, Yao C
J Orthop Surg Res . 2024 Jan; 19(1):26. PMID: 38167111
Purpose: In this study, we aimed to investigate the effects of postoperative malrotation alignment on the outcomes of Gartland type III/IV paediatric supracondylar humeral fracture (SCHF) treated by close reduction...
17.
Shi Q, Xiao K, Gao L, Wu Y, Zhou W, Liang D, et al.
China CDC Wkly . 2023 Nov; 5(43):958-965. PMID: 38025513
Introduction: Human prion diseases (PrDs) are rare, fatal encephalopathies requiring comprehensive diagnostic analysis. This study examines hospital referral patterns to the Chinese National Surveillance for Creutzfeldt-Jakob Disease (CNS-CJD) from 2006...
18.
Fan Q, Wu Y, Jia X, A R, Liu C, Zhang W, et al.
ACS Chem Neurosci . 2023 Sep; 14(20):3772-3793. PMID: 37769016
Galectin 3 (Gal-3) is one of the major elements for activating microglia and mediating neuroinflammation in some types of neurodegenerative diseases. However, its role in the pathogenesis of prion disease...
19.
Fan Q, Xiao K, A R, Gao L, Wu Y, Chen D, et al.
Mol Neurobiol . 2023 Sep; 61(12):9810-9834. PMID: 37726499
Mitochondrial dysfunction is one of the hallmarks in the pathophysiology of prion disease and other neurodegenerative diseases. Various metabolic dysfunctions are identified and considered to contribute to the progression of...
20.
Wu Y, Gao L, Chen D, Liang D, Chen J, Xiao K, et al.
Neurobiol Aging . 2023 Sep; 131:156-169. PMID: 37660403
Genetic Creutzfeldt-Jakob disease with T188K mutation (T188K gCJD) is the most frequent genetic prion disease in China. To explore the penetration of T188K mutation and the pathogenesis of T188K gCJD,...