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Canhui Zheng

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Articles 30
Citations 147
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Recent Articles
1.
Wang W, Qiu S, Zhang T, Zheng Z, Zhu K, Gao X, et al.
Eur J Med Chem . 2024 Apr; 271:116404. PMID: 38631262
Hearing loss (HL) is a health burden that seriously affects the quality of life of cancer patients receiving platinum-based chemotherapy, and few FDA-approved treatment specifically targets this condition. The main...
2.
Zheng C, Rej R, Wang M, Huang L, Fernandez-Salas E, Yang C, et al.
ACS Med Chem Lett . 2023 Oct; 14(10):1389-1395. PMID: 37849536
Lysine specific demethylase 1 (LSD1) acts as an epigenetic eraser by specifically demethylating mono- and histone 3 lysine 4 (H3K4) and H3 lysine 9 (H3K9) residues. LSD1 has been pursued...
3.
Xiong H, Lu D, Li Z, Wu J, Ning X, Lin W, et al.
Plant Commun . 2023 Apr; 4(5):100597. PMID: 37002603
Plant growth is coordinately controlled by various environmental and hormonal signals, of which light and gibberellin (GA) signals are two critical factors with opposite effects on hypocotyl elongation. Although interactions...
4.
Wu K, He R, Li Z, Qiu K, Xiao G, Peng L, et al.
Eur J Med Chem . 2023 Mar; 251:115237. PMID: 36905915
Rearranged during transfection (RET) is a promising target for antitumor drug development. Multikinase inhibitors (MKI) have been developed for RET-driven cancers but displayed limited efficacy in disease control. Two selective...
5.
Zhu D, Xiong H, Wu J, Zheng C, Lu D, Zhang L, et al.
Front Physiol . 2022 Jan; 12:802057. PMID: 35095563
In higher plants, chloroplasts are essential semi-autonomous organelles with complex compartments. As part of these sub-organellar compartments, the sheet-like thylakoid membranes contain abundant light-absorbing chlorophylls bound to the light-harvesting proteins...
6.
Zheng C, Xu X, Zhang L, Lu D
Front Physiol . 2022 Jan; 12:801212. PMID: 35002776
In higher plants, chloroplasts are vital organelles possessing highly complex compartmentalization. As most chloroplast-located proteins are encoded in the nucleus and synthesized in the cytosol, the correct sorting of these...
7.
Xu X, Zheng C, Lu D, Song C, Zhang L
J Integr Plant Biol . 2021 Jul; 63(11):1835-1855. PMID: 34314106
A fundamental challenge for cells is how to coordinate various biochemical reactions in space and time. To achieve spatiotemporal control, cells have developed organelles that are surrounded by lipid bilayer...
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Tian W, Guo J, Zhang Q, Fang S, Zhou R, Hu J, et al.
Eur J Med Chem . 2020 Dec; 212:113119. PMID: 33383258
Aldehyde dehydrogenase 2 (ALDH2) plays important role in ethanol metabolism, and also serves as an important shield from the damage occurring under oxidative stress. A special inactive variant was found...
10.
Xu X, Ouyang M, Lu D, Zheng C, Zhang L
Trends Cell Biol . 2020 Oct; 31(1):9-16. PMID: 33121860
Chloroplasts have multiple suborganellar membranes. Correct and efficient translocation of chloroplast proteins from their site of synthesis into or across membranes to their functional compartments are fundamental processes. In recent...