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Cameron D Mackereth

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Articles 55
Citations 709
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Recent Articles
1.
Bernhard H, Petrzilkova H, Popelarova B, Ziemkiewicz K, Bartosik K, Warminski M, et al.
Nat Commun . 2025 Jan; 16(1):685. PMID: 39814716
Kinetoplastids are a clade of eukaryotic protozoans that include human parasitic pathogens like trypanosomes and Leishmania species. In these organisms, protein-coding genes are transcribed as polycistronic pre-mRNAs, which need to...
2.
Swain B, Sarkis P, Ung V, Rousseau S, Fernandez L, Meltonyan A, et al.
Nat Commun . 2024 Oct; 15(1):8766. PMID: 39384813
Eukaryotic translation initiation factor eIF4B is required for efficient cap-dependent translation, it is overexpressed in cancer cells, and may influence stress granule formation. Due to the high degree of intrinsic...
3.
Kaiyum Y, Hoi Pui Chao E, Dhar L, Shoara A, Nguyen M, Mackereth C, et al.
Chembiochem . 2024 Oct; 25(23):e202400493. PMID: 39370408
Aptamers are often employed as molecular recognition elements in the development of different types of biosensors. Many of these biosensors take advantage of the aptamer having a ligand-induced structure-formation binding...
4.
Rimbault C, Breillat C, Compans B, Toulme E, Vicente F, Fernandez-Monreal M, et al.
Elife . 2024 Jan; 13. PMID: 38167295
Despite the constant advances in fluorescence imaging techniques, monitoring endogenous proteins still constitutes a major challenge in particular when considering dynamics studies or super-resolution imaging. We have recently evolved specific...
5.
Thore S, Raoelijaona F, Talenton V, Fribourg S, Mackereth C
Open Biol . 2023 Nov; 13(11):230221. PMID: 37989222
Eukaryotic pre-mRNA is processed by a large multiprotein complex to accurately cleave the 3' end, and to catalyse the addition of the poly(A) tail. Within this cleavage and polyadenylation specificity...
6.
Mondal S, Rousseau S, Talenton V, Thiam C, Aznauryan M, Mackereth C
Biomol NMR Assign . 2023 Jun; 17(2):199-203. PMID: 37368134
Translation initiation in eukaryotes is an early step in protein synthesis, requiring multiple factors to recruit the ribosomal small subunit to the mRNA 5' untranslated region. One such protein factor...
7.
Pachota M, Grzywa R, Iwanejko J, Synowiec A, Iwan D, Kaminska K, et al.
Antiviral Res . 2023 Apr; 213:105604. PMID: 37054954
Herpes simplex virus type 1 (HSV-1) is a widespread human pathogen known to cause infections of diverse severity, ranging from mild ulceration of mucosal and dermal tissues to life-threatening viral...
8.
Thore S, Fribourg S, Mackereth C
Biomol NMR Assign . 2023 Feb; 17(1):43-48. PMID: 36723825
The initial pre-mRNA transcript in eukaryotes is processed by a large multi-protein complex in order to correctly cleave the 3' end, and to subsequently add the polyadenosine tail. This cleavage...
9.
Kabbara A, Vialet B, Marquevielle J, Bonnafous P, Mackereth C, Amrane S
Front Chem . 2022 Dec; 10:1014663. PMID: 36479439
COVID-19 (Corona Virus Disease 2019), SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) are infectious diseases each caused by coronavirus outbreaks. Small molecules and other therapeutics are...
10.
Foucher A, Touat-Todeschini L, Juarez-Martinez A, Rakitch A, Laroussi H, Karczewski C, et al.
Nat Commun . 2022 Aug; 13(1):4969. PMID: 36002457
To eliminate specific or aberrant transcripts, eukaryotes use nuclear RNA-targeting complexes that deliver them to the exosome for degradation. S. pombe MTREC, and its human counterpart PAXT, are key players...