Calvin C Smith
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Explore the profile of Calvin C Smith including associated specialties, affiliations and a list of published articles.
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9
Citations
111
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Recent Articles
1.
Smith C, Nascimento F, Ozyurt M, Beato M, Brownstone R
iScience
. 2024 Aug;
27(8):110444.
PMID: 39148717
The increased muscular force output required for some behaviors is achieved via amplification of motoneuron output via cholinergic C-bouton synapses. Work in neonatal mouse motoneurons suggested that modulation of currents...
2.
Pocratsky A, Nascimento F, Ozyurt M, White I, Sullivan R, OCallaghan B, et al.
Sci Transl Med
. 2023 May;
15(694):eadg3904.
PMID: 37134150
Dystonia, a neurological disorder defined by abnormal postures and disorganized movements, is considered to be a neural circuit disorder with dysfunction arising within and between multiple brain regions. Given that...
3.
Smith C, Brownstone R
Adv Neurobiol
. 2022 Sep;
28:191-232.
PMID: 36066827
Motoneurons are the 'final common path' between the central nervous system (that intends, selects, commands, and organises movement) and muscles (that produce the behaviour). Motoneurons are not passive relays, but...
4.
Kissane R, Ghaffari-Rafi A, Tickle P, Chakrabarty S, Egginton S, Brownstone R, et al.
J Anat
. 2021 May;
241(5):1157-1168.
PMID: 33939175
Mammalian motor systems adapt to the demands of their environment. For example, muscle fibre types change in response to increased load or endurance demands. However, for adaptations to be effective,...
5.
Smith C, Brownstone R
J Physiol
. 2020 Aug;
598(23):5467-5485.
PMID: 32851667
Key Points: Many mammals are born with immature motor systems that develop through a critical period of postnatal development. In rodents, postnatal maturation of movement occurs from rostral to caudal,...
6.
Smith C, Kissane R, Chakrabarty S
eNeuro
. 2018 Nov;
5(5).
PMID: 30406182
In order to successfully perform motor tasks such as locomotion, the central nervous system must coordinate contractions of antagonistic and synergistic muscles across multiple joints. This coordination is largely dependent...
7.
Smith C, Paton J, Chakrabarty S, Ichiyama R
J Neurosci
. 2017 Jun;
37(26):6372-6387.
PMID: 28576940
The formation of mature spinal motor circuits is dependent on both activity-dependent and independent mechanisms during postnatal development. During this time, reorganization and refinement of spinal sensorimotor circuits occurs as...
8.
Chen K, Marsh B, Cowan M, Aljoboori Y, Gigout S, Smith C, et al.
Exp Neurol
. 2017 Mar;
292:135-144.
PMID: 28341461
Intense training is the most clinically successful treatment modality following incomplete spinal cord injuries (SCIs). With the advent of plasticity enhancing treatments, understanding how treatments might interact when delivered in...
9.
Smith C, Mauricio R, Nobre L, Marsh B, Wust R, Rossiter H, et al.
Brain Res Bull
. 2014 Dec;
111:20-6.
PMID: 25526898
Perineuronal nets (PNNs) are lattice like structures which encapsulate the cell body and proximal dendrites of many neurons and are thought to be involved in regulating synaptic plasticity. It is...