Caitlin S Latimer
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Explore the profile of Caitlin S Latimer including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Latimer C, Prater K, Postupna N, Keene C
Cold Spring Harb Perspect Med
. 2023 Dec;
14(8).
PMID: 38151325
Dementia is a significant public health crisis; the most common underlying cause of age-related cognitive decline and dementia is Alzheimer's disease neuropathologic change (ADNC). As such, there is an urgent...
12.
Kundu S, Barsoum S, Ariza J, Nolan A, Latimer C, Keene C, et al.
Brain Commun
. 2023 Nov;
5(6):fcad258.
PMID: 37953850
Human evolution has seen the development of higher-order cognitive and social capabilities in conjunction with the unique laminar cytoarchitecture of the human cortex. Moreover, early-life cortical maldevelopment has been associated...
13.
Huang Z, Merrihew G, Larson E, Park J, Plubell D, Fox E, et al.
Neurosci Insights
. 2023 Oct;
18:26331055231201600.
PMID: 37810186
Studying proteomics data of the human brain could offer numerous insights into unraveling the signature of resilience to Alzheimer's disease. In our previous study with rigorous cohort selection criteria that...
14.
Berson E, Gajera C, Phongpreecha T, Perna A, Bukhari S, Becker M, et al.
Sci Rep
. 2023 Aug;
13(1):13849.
PMID: 37620363
Comparing brain structure across species and regions enables key functional insights. Leveraging publicly available data from a novel mass cytometry-based method, synaptometry by time of flight (SynTOF), we applied an...
15.
Gazula H, Tregidgo H, Billot B, Balbastre Y, William-Ramirez J, Herisse R, et al.
bioRxiv
. 2023 Jun;
PMID: 37333251
We present open-source tools for 3D analysis of photographs of dissected slices of human brains, which are routinely acquired in brain banks but seldom used for quantitative analysis. Our tools...
16.
Gabitto M, Travaglini K, Rachleff V, Kaplan E, Long B, Ariza J, et al.
Res Sq
. 2023 Jun;
PMID: 37292694
Alzheimer's disease (AD) is the most common cause of dementia in older adults. Neuropathological and imaging studies have demonstrated a progressive and stereotyped accumulation of protein aggregates, but the underlying...
17.
Maioli H, Mittenzwei R, Shofer J, Scherpelz K, Marshall D, Nolan A, et al.
J Neuropathol Exp Neurol
. 2023 May;
82(7):611-619.
PMID: 37195467
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is a dementia-related proteinopathy common in the elderly population. LATE-NC stages 2 or 3 are consistently associated with cognitive impairment. A condensed protocol...
18.
Huang Z, Merrihew G, Larson E, Park J, Plubell D, Fox E, et al.
Nat Commun
. 2023 May;
14(1):2747.
PMID: 37173305
Resilience to Alzheimer's disease is an uncommon combination of high disease burden without dementia that offers valuable insights into limiting clinical impact. Here we assessed 43 research participants meeting stringent...
19.
Gibbons L, Power M, Walker R, Kumar R, Murphy A, Latimer C, et al.
J Alzheimers Dis
. 2023 May;
93(3):949-961.
PMID: 37125552
Background: Prior studies into the association of head trauma with neuropathology have been limited by incomplete lifetime neurotrauma exposure characterization. Objective: To investigate the neuropathological sequelae of traumatic brain injury...
20.
Nichols E, Merrick R, Hay S, Himali D, Himali J, Hunter S, et al.
Lancet Healthy Longev
. 2023 Mar;
4(3):e115-e125.
PMID: 36870337
Background: Population-based autopsy studies provide valuable insights into the causes of dementia but are limited by sample size and restriction to specific populations. Harmonisation across studies increases statistical power and...