C Waghorne
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Explore the profile of C Waghorne including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
414
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Recent Articles
1.
Yagel S, Feinmesser R, Waghorne C, Lala P, Breitman M, Dennis J
Int J Cancer
. 1989 Oct;
44(4):685-90.
PMID: 2507455
In previous studies we have shown that the ability of murine tumor cells to metastasize in situ is directly linked to expression of -GlcNAc beta 1-6Man alpha 1-6Man beta 1-branched...
2.
Yagel S, WARNER A, Nellans H, Lala P, Waghorne C, Denhardt D
Cancer Res
. 1989 Jul;
49(13):3553-7.
PMID: 2731177
Cysteine proteinases, particularly cathepsins B and L, have been strongly implicated in fostering metastasis in mice. In this work four different inhibitors of cysteine proteinases have been shown to inhibit...
3.
Waghorne C, Thomas M, Lagarde A, Kerbel R, Breitman M
Cancer Res
. 1988 Nov;
48(21):6109-14.
PMID: 3167857
We have exploited random insertions of transfected DNA as unique clonotypic markers to follow cell lineages during primary and metastatic tumor growth of a mouse mammary adenocarcinoma, SP1. Southern analysis...
4.
Kerbel R, Waghorne C, Korczak B, Lagarde A, Breitman M
Cancer Surv
. 1988 Jan;
7(4):597-629.
PMID: 3072068
A new method is described for analysing the clonal evolutionary dynamics of tumour growth and the lineage relationship of primary tumours to their metastases. It exploits random integrations of transfected...
5.
Kerbel R, Waghorne C, Korczak B, Breitman M
Ciba Found Symp
. 1988 Jan;
141:123-48.
PMID: 2855413
We have exploited random integrations of foreign DNA as a means of genetically tagging tumour cell populations with which to analyse the clonal evolution of tumour growth in vivo. Transfection...
6.
Waghorne C, Korczak B, Breitman M, Kerbel R
Adv Exp Med Biol
. 1988 Jan;
233:27-37.
PMID: 2851927
No abstract available.
7.
Waghorne C, Kerbel R, Breitman M
Oncogene
. 1987 May;
1(2):149-55.
PMID: 3325879
The mouse mammary adenocarcinoma cell line SP1 was transfected with either the activated T24-H-ras or the normal c-H-ras gene and assessed for metastatic potential in syngeneic CBA/J or nude mice....
8.
Dennis J, Laferte S, Waghorne C, Breitman M, Kerbel R
Science
. 1987 May;
236(4801):582-5.
PMID: 2953071
Neoplastic transformation has been associated with a variety of structural changes in cell surface carbohydrates, most notably increased sialylation and beta 1-6-linked branching of complex-type asparagine (Asn)-linked oligosaccharides (that is,...
9.
Kerbel R, Waghorne C, Man M, Elliott B, Breitman M
Proc Natl Acad Sci U S A
. 1987 Mar;
84(5):1263-7.
PMID: 3469668
During the course of studies designed to assess the effect of human Ha-ras gene expression on the malignant behavior of transfected mouse tumor cells we noted that the process of...
10.
Waghorne C, Fuerst C
J Bacteriol
. 1985 Nov;
164(2):960-3.
PMID: 2932429
A new mutation in the htpR (rpoH) gene of Escherichia coli K-12 was identified. The mutation resulted in a temperature-sensitive phenotype in terms of cell growth and bacteriophage lambda development....