C von Kobbe
Overview
Explore the profile of C von Kobbe including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
1058
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0
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Recent Articles
1.
Spillare E, Wang X, von Kobbe C, Bohr V, Hickson I, Harris C
Oncogene
. 2005 Nov;
25(14):2119-23.
PMID: 16288211
A subset of DNA helicases, the RecQ family, has been found to be associated with the p53-mediated apoptotic pathway and is involved in maintaining genomic integrity. This family contains the...
2.
Brosh Jr R, von Kobbe C, Sommers J, Karmakar P, Opresko P, Piotrowski J, et al.
EMBO J
. 2001 Oct;
20(20):5791-801.
PMID: 11598021
Werner syndrome (WS) is a human premature aging disorder characterized by chromosomal instability. The cellular defects of WS presumably reflect compromised or aberrant function of a DNA metabolic pathway that...
3.
Bachi A, Braun I, Rodrigues J, Pante N, Ribbeck K, von Kobbe C, et al.
RNA
. 2000 Feb;
6(1):136-58.
PMID: 10668806
Messenger RNAs are exported from the nucleus as large ribonucleoprotein complexes (mRNPs). To date, proteins implicated in this process include TAP/Mex67p and RAE1/Gle2p and are distinct from the nuclear transport...
4.
Schmitt C, von Kobbe C, Bachi A, Pante N, Rodrigues J, Boscheron C, et al.
EMBO J
. 1999 Aug;
18(15):4332-47.
PMID: 10428971
Dbp5 is a DEAD-box protein essential for mRNA export from the nucleus in yeast. Here we report the isolation of a cDNA encoding human Dbp5 (hDbp5) which is 46% identical...
5.
Gruter P, Tabernero C, von Kobbe C, Schmitt C, Saavedra C, Bachi A, et al.
Mol Cell
. 1998 Jul;
1(5):649-59.
PMID: 9660949
The constitutive transport element (CTE) of the type D retroviruses promotes nuclear export of unspliced viral RNAs apparently by recruiting host factor(s) required for export of cellular messenger RNAs. Here,...
6.
Jimenez C, Jones D, Rodriguez-Viciana P, Gonzalez-Garcia A, Leonardo E, Wennstrom S, et al.
EMBO J
. 1998 Mar;
17(3):743-53.
PMID: 9450999
p85/p110 phosphoinositide 3-kinase (PI3K) is a heterodimer composed of a p85-regulatory and a p110-catalytic subunit, which is involved in a variety of cellular responses including cytoskeletal organization, cell survival and...
7.
Izaurralde E, Kutay U, von Kobbe C, Mattaj I, Gorlich D
EMBO J
. 1997 Nov;
16(21):6535-47.
PMID: 9351834
The GTPase Ran is essential for nuclear import of proteins with a classical nuclear localization signal (NLS). Ran's nucleotide-bound state is determined by the chromatin-bound exchange factor RCC1 generating RanGTP...
8.
Mellado M, Rodriguez-Frade J, Kremer L, von Kobbe C, de Ana A, Merida I, et al.
J Biol Chem
. 1997 Apr;
272(14):9189-96.
PMID: 9083050
Growth hormone (GH) plays a significant role in normal growth and development. Signaling to the cell is believed to require growth hormone receptor (GHR) dimerization, which occurs following binding of...
9.
Gonzalo J, Mazuchelli R, Mellado M, Frade J, Carrera A, von Kobbe C, et al.
J Immunol
. 1996 Oct;
157(8):3298-304.
PMID: 8871624
Neuroendocrine hormones have long been thought to play a role in lymphoid development and function. In particular, growth hormone has been shown to mediate thymic development as well as to...