C Toniatti
Overview
Explore the profile of C Toniatti including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1162
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Recent Articles
1.
Savino R, Demartis A, Ciapponi L, Sporeno E, Toniatti C, Bernassola F, et al.
Oncol Rep
. 2011 May;
4(3):485-92.
PMID: 21590082
Interleukin-6 (IL-6) plays a central role in the pathogenesis of multiple myeloma, acting both as a growth and a survival factor for myeloma cells. IL-6 has been recently shown to...
2.
Dharmapuri S, Peruzzi D, Marra E, Palombo F, Bett A, Bartz S, et al.
Gene Ther
. 2011 Mar;
18(7):727-33.
PMID: 21390070
Small interfering RNAs (siRNAs) are emerging as promising therapeutic tools. However, the widespread clinical application of such molecules as modulators of gene expression is still dependent on several aspects that...
3.
Toniatti C, Bujard H, Cortese R, Ciliberto G
Gene Ther
. 2004 Feb;
11(8):649-57.
PMID: 14985790
The clinical efficacy and safety as well as the application range of gene therapy will be broadened by developing systems capable of finely modulating the expression of therapeutic genes. Transgene...
4.
Salucci V, Scarito A, Aurisicchio L, Lamartina S, Nicolaus G, Giampaoli S, et al.
Gene Ther
. 2002 Oct;
9(21):1415-21.
PMID: 12378403
Control of gene expression for gene therapy application requires the design of a sophisticated system embodying multiple properties. The ideal system should present the following features: (1) low or undetectable...
5.
Samakoglu S, Fattori E, Lamartina S, Toniatti C, Stockholm D, Heard J, et al.
Blood
. 2001 Apr;
97(8):2213-20.
PMID: 11290581
Mechanisms governing the induction of effective erythropoiesis in response to erythropoietin (Epo) oversecretion have been investigated in beta thalassemic C57Bl/6(Hbbth) mice. Naked DNA encoding an expression vector for mouse Epo...
6.
Lamartina S, Ciliberto G, Toniatti C
J Virol
. 2000 Sep;
74(19):8831-42.
PMID: 10982325
The adeno-associated virus type 2 (AAV-2) Rep78 and Rep68 proteins are required for replication of the virus as well as its site-specific integration into a unique site, called AAVS1, of...
7.
8.
Lamartina S, Sporeno E, Fattori E, Toniatti C
J Virol
. 2000 Jul;
74(16):7671-7.
PMID: 10906224
Adeno-associated virus (AAV) establishes latency in infected cells by integrating into the cellular genome, with a high preference for a unique region, called AAVS1, of the human chromosome 19. The...
9.
Rinaudo D, Lamartina S, Roscilli G, Ciliberto G, Toniatti C
J Virol
. 1999 Dec;
74(1):281-94.
PMID: 10590116
It is of great interest for gene therapy to develop vectors that drive the insertion of a therapeutic gene into a chosen specific site on the cellular genome. Adeno-associated virus...
10.
Recchia A, Parks R, Lamartina S, Toniatti C, Pieroni L, Palombo F, et al.
Proc Natl Acad Sci U S A
. 1999 Mar;
96(6):2615-20.
PMID: 10077559
Adenovirus (Ad) and adeno-associated virus (AAV) have attractive and complementary properties that can be exploited for gene transfer purposes. Ad vectors are probably the most efficient vehicles to deliver foreign...