E Sporeno
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Explore the profile of E Sporeno including associated specialties, affiliations and a list of published articles.
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10
Citations
118
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Recent Articles
1.
Savino R, Demartis A, Ciapponi L, Sporeno E, Toniatti C, Bernassola F, et al.
Oncol Rep
. 2011 May;
4(3):485-92.
PMID: 21590082
Interleukin-6 (IL-6) plays a central role in the pathogenesis of multiple myeloma, acting both as a growth and a survival factor for myeloma cells. IL-6 has been recently shown to...
2.
Fattori E, Zampaglione I, Arcuri M, Meola A, Ercole B, Cirillo A, et al.
Gene Ther
. 2006 Mar;
13(14):1088-96.
PMID: 16554842
Efficient vaccination against viral agents requires a strong T-cell-mediated immune response to clear viral-infected cells. Optimal vaccination can be achieved by administration of recombinant viral vectors encoding phatogen antigens. Adenoviral...
3.
Lamartina S, Sporeno E, Fattori E, Toniatti C
J Virol
. 2000 Jul;
74(16):7671-7.
PMID: 10906224
Adeno-associated virus (AAV) establishes latency in infected cells by integrating into the cellular genome, with a high preference for a unique region, called AAVS1, of the human chromosome 19. The...
4.
Sporeno E, Savino R, Ciapponi L, Paonessa G, Cabibbo A, Lahm A, et al.
Blood
. 1996 Jun;
87(11):4510-9.
PMID: 8639818
Interleukin-6 (IL-6) is the major growth factor for myeloma cells and is believed to participate in the pathogenesis of chronic autoimmune diseases and postmenopausal osteoporosis. IL-6 has been recently shown...
5.
Cabibbo A, Sporeno E, Toniatti C, Altamura S, Savino R, Paonessa G, et al.
Gene
. 1995 Dec;
167(1-2):41-7.
PMID: 8566809
Phage display of proteins can be used to study ligand-receptor interaction and for the affinity-maturation of binding sites in polypeptide hormones and/or cytokines. We have expressed human interleukin-6 (hIL-6) on...
6.
Sporeno E, Barbato G, Graziani R, Pucci P, NITTI G, Paonessa G
Cytokine
. 1994 May;
6(3):255-64.
PMID: 8054481
Oncostatin M is a cytokine that acts as a growth regulator on a wide variety of cells and has diverse biological activities including acute phase protein induction, LDL receptor up-regulation...
7.
Sporeno E, Paonessa G, Salvati A, Graziani R, DELMASTRO P, Ciliberto G, et al.
J Biol Chem
. 1994 Apr;
269(15):10991-5.
PMID: 8157624
Oncostatin M (OM) and interleukin 6 (IL-6) are functionally related cytokines, which trigger similar biological responses because they share gp130 as a common signal transducing transmembrane receptor. While IL-6 recruits...
8.
Savino R, Lahm A, Salvati A, Ciapponi L, Sporeno E, Altamura S, et al.
EMBO J
. 1994 Mar;
13(6):1357-67.
PMID: 7511100
Interleukin-6 (IL-6) drives the sequential assembly of a receptor complex formed by the IL-6 receptor (IL-6R alpha) and the signal transducing subunit, gp130. A model of human IL-6 (hIL-6) was...
9.
Gigliani F, Sporeno E, Perri S, Battaglia P
Mol Gen Genet
. 1989 Jul;
218(1):18-24.
PMID: 2550763
We show that a DNA fragment that contains the uvp1 gene of the plasmid pR directs the synthesis in Escherichia coli minicells of a protein of apparent molecular weight 20...
10.
Cellular response to DNA damage is enhanced by the pR plasmid in mouse cells and in Escherichia coli
Marcucci L, Gigliani F, Battaglia P, BOSI R, Sporeno E, Elli R
Mol Cell Biol
. 1986 Feb;
6(2):586-92.
PMID: 3023858
The pR plasmid, which enhances the survival of Escherichia coli C600 exposed to UV light by induction of the SOS regulatory mechanism, showed the same effect when it transformed mouse...