C Theo Verrips
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Explore the profile of C Theo Verrips including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
772
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Recent Articles
11.
Optimizing immuno-labeling for correlative fluorescence and electron microscopy on a single specimen
Karreman M, Agronskaia A, van Donselaar E, Vocking K, Fereidouni F, Humbel B, et al.
J Struct Biol
. 2012 Sep;
180(2):382-6.
PMID: 22982545
Correlative fluorescence and electron microscopy has become an indispensible tool for research in cell biology. The integrated Laser and Electron Microscope (iLEM) combines a Fluorescence Microscope (FM) and a Transmission...
12.
Summanen M, Granqvist N, Tuominen R, Yliperttula M, Verrips C, Boonstra J, et al.
PLoS One
. 2012 Apr;
7(4):e35630.
PMID: 22536418
Dysregulation of PKCε is involved in several serious diseases such as cancer, type II diabetes and Alzheimer's disease. Therefore, specific activators and inhibitors of PKCε hold promise as future therapeutics,...
13.
Brummelhuis W, Joles J, Stam J, Verrips C, Braam B
Shock
. 2011 Dec;
37(3):247-52.
PMID: 22129566
Severe sepsis is characterized by rapid development of multiple organ failure associated with high mortality. Bacterial toxin release triggers a sequence of events that activates intracellular pathways to produce inflammatory...
14.
Emmerson C, van der Vlist E, Braam M, Vanlandschoot P, Merchiers P, De Haard H, et al.
PLoS One
. 2011 Oct;
6(10):e26299.
PMID: 22022593
The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and...
15.
Hultberg A, Temperton N, Rosseels V, Koenders M, Gonzalez-Pajuelo M, Schepens B, et al.
PLoS One
. 2011 Apr;
6(4):e17665.
PMID: 21483777
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins...
16.
Karreman M, van Donselaar E, Gerritsen H, Verrips C, Verkleij A
Traffic
. 2011 Apr;
12(7):806-14.
PMID: 21449950
Immuno-transmission electron microscopy (TEM) is the technique of choice for high-resolution localization of proteins in fixed specimen. Here we introduce 2 novel methods for the fixation of sections from cryo-immobilized...
17.
Paalanen M, Ekokoski E, El Khattabi M, Tuominen R, Verrips C, Boonstra J, et al.
Eur J Pharm Sci
. 2011 Jan;
42(4):332-9.
PMID: 21220006
The 10 isozymes of the protein kinase C (PKC) family can have different roles on the same biological process, making isozyme specific analysis of function crucial. Currently, only few pharmacological...
18.
Brummelhuis W, Joles J, Stam J, Adams H, Goldschmeding R, Detmers F, et al.
Shock
. 2009 Dec;
34(2):125-32.
PMID: 20016410
Staphylococcus aureus produces the superantigen toxic shock syndrome toxin 1 (TSST-1). When the bacterium invades the human circulation, this toxin can induce life-threatening gram-positive sepsis. Current sepsis treatment does not...
19.
Rutgers K, van Remoortere A, van Buchem M, Verrips C, Greenberg S, Bacskai B, et al.
Neurobiol Aging
. 2009 Dec;
32(10):1774-83.
PMID: 20015576
By phage display, llama-derived heavy chain antibody fragments were selected from non-immune and immune libraries and tested for their affinity and specificity for beta amyloid by phage-ELISA, immunohistochemistry and surface...
20.
Groot A, El Khattabi M, Sachs N, van der Groep P, van der Wall E, van Diest P, et al.
Mol Immunol
. 2009 Apr;
46(10):2022-8.
PMID: 19359042
Therapeutic approaches aimed at targeting tumor surface markers using monoclonal antibodies provide a powerful strategy in cancer treatment. Here we report selection of single variable domains (VHH) of llama heavy...