C Schalk-Hihi
Overview
Explore the profile of C Schalk-Hihi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
182
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Greco M, Connelly M, Leo G, Olson M, Powell E, Huang Z, et al.
Bioorg Med Chem Lett
. 2013 Mar;
23(9):2595-7.
PMID: 23528297
By screening directed libraries of serine hydrolase inhibitors using the cell surface form of endothelial lipase (EL), we identified a series of carbamate-derived (EL) inhibitors. Compound 3 raised plasma HDL-C...
2.
Graham D, Bock C, Schalk-Hihi C, Lu Z, Markham G
J Biol Chem
. 2000 Feb;
275(6):4055-9.
PMID: 10660563
S-adenosylmethionine is the primary alkylating agent in all known organisms. ATP:L-methionine S-adenosyltransferase (MAT) catalyzes the only known biosynthetic route to this central metabolite. Although the amino acid sequence of MAT...
3.
Hoover D, Schalk-Hihi C, Chou C, Menon S, Wlodawer A, Zdanov A
Eur J Biochem
. 1999 May;
262(1):134-41.
PMID: 10231374
Interleukin-10 (IL-10) is a pleiotropic immunosuppressive cytokine that has a wide range of effects in controlling inflammatory responses. Viral IL-10 (vIL-10) is a homologue of human IL-10 (hIL-10) produced by...
4.
Markham G, Bock C, Schalk-Hihi C
Biochemistry
. 1999 Apr;
38(14):4433-40.
PMID: 10194364
Inosine-5'-monophosphate dehydrogenase (IMPDH) catalyzes the K+-dependent reaction IMP + NAD + H2O --> XMP + NADH + H+ which is the rate-limiting step in guanine nucleotide biosynthesis. The catalytic mechanism...
5.
Schalk-Hihi C, Markham G
Biochemistry
. 1999 Feb;
38(8):2542-50.
PMID: 10029549
S-Adenosylmethionine (AdoMet) is the most widely used alkyl group donor in biological systems. The formation of AdoMet from ATP and L-methionine is catalyzed by S-adenosylmethionine synthetase (AdoMet synthetase). Elucidation of...
6.
Schalk-Hihi C, Zhang Y, Markham G
Biochemistry
. 1998 Jun;
37(20):7608-16.
PMID: 9585576
Inosine 5'-monophosphate dehydrogenase (IMPDH) catalyzes the oxidation of inosine 5-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP). The reaction proceeds with concomitant conversion of NAD+ to NADH and is the rate-limiting step...
7.
Laco G, Schalk-Hihi C, Lubkowski J, Morris G, Zdanov A, Olson A, et al.
Biochemistry
. 1997 Sep;
36(35):10696-708.
PMID: 9271500
Crystal structures of complexes of a D30N mutant of feline immunodeficiency virus protease (FIV PR) complexed with a statine-based inhibitor (LP-149), as well as with a substrate based on a...
8.
Zdanov A, Schalk-Hihi C, Menon S, Moore K, Wlodawer A
J Mol Biol
. 1997 May;
268(2):460-7.
PMID: 9159483
The crystal structure of Epstein-Barr virus protein BCRF1, an analog of cellular interleukin-10 (IL-10), has been determined at the resolution of 1.9 A and refined to an R-factor 0.191. The...
9.
Zdanov A, Schalk-Hihi C, Wlodawer A
Protein Sci
. 1996 Oct;
5(10):1955-62.
PMID: 8897595
The crystal structure of human interleukin-10 (IL-10) was refined at 1.6 A resolution against X-ray diffraction data collected at 100 K with the use of synchrotron radiation. Although similar to...
10.
Zdanov A, Schalk-Hihi C, Gustchina A, Tsang M, Weatherbee J, Wlodawer A
Structure
. 1995 Jun;
3(6):591-601.
PMID: 8590020
Background: Interleukin (IL)-10 is a cytokine that inhibits production of other regulatory factors, including interferon gamma (IFN-gamma) and IL-2. A dimer of IL-10 is present in solution and is presumed...