C Nerlov
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Explore the profile of C Nerlov including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
1125
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Recent Articles
1.
Reckzeh K, Bereshchenko O, Mead A, Rehn M, Kharazi S, Jacobsen S, et al.
Leukemia
. 2012 Feb;
26(7):1527-36.
PMID: 22318449
Biallelic CEBPA mutations and FMS-like tyrosine kinase receptor 3 (FLT3) length mutations are frequently identified in human acute myeloid leukemia (AML) with normal cytogenetics. However, the molecular and cellular mechanisms...
2.
Fujimoto T, Anderson K, Jacobsen S, Nishikawa S, Nerlov C
EMBO J
. 2007 Apr;
26(9):2361-70.
PMID: 17431401
Interactions between the cell cycle machinery and transcription factors play a central role in coordinating terminal differentiation and proliferation arrest. We here show that cyclin-dependent kinase 6 (Cdk6) is specifically...
3.
PEDERSEN T, Kowenz-Leutz E, Leutz A, Nerlov C
Genes Dev
. 2001 Dec;
15(23):3208-16.
PMID: 11731483
Chromatin remodeling is an important step in promoter activation during cellular lineage commitment and differentiation. We show that the ability of the C/EBPalpha transcription factor to direct adipocyte differentiation of...
4.
Porse B, Pedersen TA , Xu X, Lindberg B, Wewer U, Friis-Hansen L, et al.
Cell
. 2001 Oct;
107(2):247-58.
PMID: 11672531
The C/EBPalpha transcription factor is required for differentiation of adipocytes and neutrophil granulocytes, and controls cellular proliferation in vivo. To address the molecular mechanisms of C/EBPalpha action, we have identified...
5.
Nerlov C, Querfurth E, Kulessa H, Graf T
Blood
. 2001 Feb;
95(8):2543-51.
PMID: 10753833
The GATA-1 transcription factor is capable of suppressing the myeloid gene expression program when ectopically expressed in myeloid cells. We examined the ability of GATA-1 to repress the expression and...
6.
Querfurth E, Schuster M, Kulessa H, Crispino J, DODERLEIN G, Orkin S, et al.
Genes Dev
. 2000 Oct;
14(19):2515-25.
PMID: 11018018
The commitment of multipotent cells to particular developmental pathways requires specific changes in their transcription factor complement to generate the patterns of gene expression characteristic of specialized cell types. We...
7.
Rourke I, Hansen T, Nerlov C, Rehfeld J, Nielsen F
FEBS Lett
. 1999 Apr;
448(1):15-8.
PMID: 10217400
The promoter of the cholecystokinin (CCK) gene possesses evolutionary conserved juxtaposed E-box and cAMP/TPA responsive elements (CRE/TRE). We have examined the functional interaction of these two sites. As previously noted,...
8.
Nerlov C, McNagny K, DODERLEIN G, Kowenz-Leutz E, Graf T
Genes Dev
. 1998 Aug;
12(15):2413-23.
PMID: 9694805
Hematopoietic differentiation involves the commitment of multipotent progenitors to a given lineage, followed by the maturation of the committed cells. To study the transcriptional events controlling these processes, we have...
9.
Nerlov C, Graf T
Genes Dev
. 1998 Aug;
12(15):2403-12.
PMID: 9694804
Little is known about the transcription factors that mediate lineage commitment of multipotent hematopoietic precursors. One candidate is the Ets family transcription factor PU.1, which is expressed in myeloid and...
10.
McNagny K, Sieweke M, DODERLEIN G, Graf T, Nerlov C
EMBO J
. 1998 Jul;
17(13):3669-80.
PMID: 9649437
The EOS47 antigen is an early and specific marker of eosinophil differentiation in the chicken haematopoietic system. To elucidate the transciptional events controlling commitment to the eosinophil lineage, we studied...