C M Tyree
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Explore the profile of C M Tyree including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
171
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Recent Articles
1.
Elmore S, Coghlan M, Anderson D, Pratt J, GREEN B, Wang A, et al.
J Med Chem
. 2001 Dec;
44(25):4481-91.
PMID: 11728194
The preparation and characterization of a series of selective glucocorticoid receptor modulators are described. The preliminary structure-activity relationship of nonaromatic C-5 substitution on the tetracyclic quinoline core showed a preference...
2.
Miner J, Tyree C
Vitam Horm
. 2001 May;
62:253-80.
PMID: 11345901
Drug discovery using intracellular receptors (IRs) as targets presents its own set of unique complications and advantages. The natural ligands for these receptors are, in many cases, already used as...
3.
FRANK D, Tyree C, George C, Kadonaga J
J Biol Chem
. 1995 Mar;
270(11):6292-7.
PMID: 7890767
To study the mechanism of basal transcription by RNA polymerase II, a cDNA encoding the Drosophila homologue of the small subunit of TFIIF (also referred to as TFIIF30, RAP30, factor...
4.
Zamrod Z, Tyree C, Song Y, Stumph W
Mol Cell Biol
. 1993 Sep;
13(9):5918-27.
PMID: 8355718
Transcription of a Drosophila U1 small nuclear RNA gene was functionally analyzed in cell extracts derived from 0- to 12-h embryos. Two promoter elements essential for efficient initiation of transcription...
5.
Tyree C, George C, Wampler S, Dahmus M, Zawel L, Kadonaga J
Genes Dev
. 1993 Jul;
7(7A):1254-65.
PMID: 8319911
In eukaryotes, initiation of mRNA synthesis is a multistep process that is carried out by RNA polymerase II and auxiliary factors that are commonly referred to as basal or general...
6.
Kamakaka R, Tyree C, Kadonaga J
Proc Natl Acad Sci U S A
. 1991 Feb;
88(3):1024-8.
PMID: 1992453
We describe the preparation and biochemical properties of a soluble nuclear fraction derived from Drosophila embryos. This extract, which can be easily prepared in 2.5 hr, is capable of accurate...
7.
Wampler S, Tyree C, Kadonaga J
J Biol Chem
. 1990 Dec;
265(34):21223-31.
PMID: 2250021
We have subdivided the components of the basic RNA polymerase II machinery from Drosophila embryos into three fractions and RNA polymerase II. The RNA polymerase II was 90% homogeneous and...