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C M Adeyeye

Explore the profile of C M Adeyeye including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 45
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Recent Articles
1.
Ebube N, Adeyeye C
Int J Pharm . 2000 Feb; 196(1):27-35. PMID: 10675705
The utility of artificial neural networks (ANNs) as a preformulation tool to determine the physicochemical properties of amorphous polymers such as the hydration characteristics, glass transition temperatures and rheological properties...
2.
Sabnis S, Adeyeye C
Drug Dev Ind Pharm . 1999 Mar; 25(2):187-96. PMID: 10065352
Directly compressible controlled-release (CR) theophylline tablet formulations with a non-zero-order drug release were prepared using various grades of Methocels. These tablet formulations were employed in the individualization of therapy with...
3.
Janjikhel R, Adeyeye C
Pharm Dev Technol . 1999 Feb; 4(1):9-17. PMID: 10027208
The purpose of this research was to evaluate the stereospecific interaction of ibuprofen with chiral excipients such as hydroxypropyl-beta-cyclodextrin (HPCD), tartaric acid, sucrose, hydroxypropylmethylcellulose (HPMC), methylcellulose (MC), and a nonchiral...
4.
Lewis L, Boni R, Adeyeye C
J Microencapsul . 1998 Sep; 15(5):555-67. PMID: 9743912
The major challenge in liquid sustained-release oral suspensions is to minimize drug diffusion into the suspending medium and to retain the original properties of the microparticles during storage. Diclofenac wax...
5.
Lewis L, Boni R, Adeyeye C
J Microencapsul . 1998 Jun; 15(3):283-98. PMID: 9608393
This investigation involved the evaluation of the emulsifier blend effect on the development of sustained release diclofenac microspheres intended for use in a suspension formulation. The microspheres were prepared using...
6.
Adeyeye C, Chen F
Pharm Res . 1998 Feb; 14(12):1811-6. PMID: 9453073
Purpose: The aim of the study is to evaluate stereoselective in vivo disposition of suspensions of conventional and wax-matrix sustained release ibuprofen microspheres in rats. Methods: Male wistar rats were...
7.
Janjikhel R, Adeyeye C
J Microencapsul . 1997 Jul; 14(4):409-26. PMID: 9229341
Ibuprofen microspheres were prepared from the racemate, (+)-S and (-)-R enantiomers using waxes such as ceresine and glyceryl stearate and stereospecifically characterized. The method of preparation of the microspheres was...
8.
Adeyeye C, Price J
J Microencapsul . 1997 May; 14(3):357-77. PMID: 9147285
Chemical stability studies of suspensions of ibuprofen powder and ibuprofen-wax microspheres were performed using an accelerated stability protocol with a modified high performance liquid chromatography (HPLC) procedure. The variables considered...
9.
Wipf P, Li W, Adeyeye C, Rusnak J, Lazo J
Bioorg Med Chem . 1996 Oct; 4(10):1585-96. PMID: 8931928
N4-Dipeptidyl slow-release forms of the anticancer drug ara-C were prepared by acylation of the lithiated nucleotide with 4,4-dialkyloxazolinones. An azapeptide prodrug of ara-C was obtained by condensation of an amino...
10.
Adeyeye C, BRICKER J, Vilivalam V, Smith W
Pharm Res . 1996 May; 13(5):784-93. PMID: 8860438
Purpose: The study examined the gastrointestinal (GIT) toxicity effects of suspensions of encapsulated and unencapsulated ibuprofen in male Wistar rats. Methods: Rats were randomly divided into four experimental groups and...