C L Mahaffey
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Explore the profile of C L Mahaffey including associated specialties, affiliations and a list of published articles.
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6
Citations
345
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Recent Articles
1.
Wagnon J, Mahaffey C, Sun W, Yang Y, Chao H, Frankel W
Genes Brain Behav
. 2011 Jul;
10(7):765-77.
PMID: 21745337
Mice deficient for the gene encoding the RNA-binding protein CELF4 (CUGBP, ELAV-like family member 4) have a complex seizure phenotype that includes both convulsive and non-convulsive seizures, depending upon gene...
2.
Frankel W, Yang Y, Mahaffey C, Beyer B, OBrien T
Genes Brain Behav
. 2009 Jul;
8(5):568-76.
PMID: 19624305
In a chemical mutagenesis screen we identified Szt2 (seizure threshold 2) as a gene that confers low seizure threshold to mice and may also enhance epileptogenesis. The semidominant phenotype was...
3.
Cox G, Mahaffey C, Nystuen A, Letts V, Frankel W
Nat Genet
. 2000 Oct;
26(2):198-202.
PMID: 11017077
The mouse mutation fidget arose spontaneously in a heterogeneous albino stock. This mutant mouse is characterized by a side-to-side head-shaking and circling behaviour, due to reduced or absent semicircular canals....
4.
Cox G, Mahaffey C, Frankel W
Neuron
. 1999 Jan;
21(6):1327-37.
PMID: 9883726
The nmd mouse mutation causes progressive degeneration of spinal motor neurons and muscle atrophy. We identified the mutated gene as the putative transcriptional activator and ATPase/DNA helicase previously described as...
5.
Letts V, Felix R, Biddlecome G, Arikkath J, Mahaffey C, Valenzuela A, et al.
Nat Genet
. 1998 Aug;
19(4):340-7.
PMID: 9697694
Stargazer mice have spike-wave seizures characteristic of absence epilepsy, with accompanying defects in the cerebellum and inner ear. We describe here a novel gene, Cacng2, whose expression is disrupted in...
6.
Mahaffey C, Bayleran J, Yeh G, Lee T, Page D, Simpson E
Genomics
. 1997 Apr;
41(1):123-7.
PMID: 9126493
Zfy1 and Zfy2 are homologous zinc finger genes on the mouse Y Chromosome. To ask whether these genes are properly classified as members of the ZFY family, we have characterized...