C K Jayawickreme
Overview
Explore the profile of C K Jayawickreme including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
175
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Recent Articles
1.
Covington D, Briscoe C, Brown A, Jayawickreme C
Biochem Soc Trans
. 2006 Oct;
34(Pt 5):770-3.
PMID: 17052194
Recent deorphanization efforts have paired the G-protein-coupled receptors GPR40, GPR41 and GPR43 with fatty acids as endogenous ligands. While carboxylic acids have been historically known to serve as fuel sources...
2.
Jayawickreme C, Sauls H, Bolio N, Ruan J, Moyer M, Burkhart W, et al.
J Pharmacol Toxicol Methods
. 2000 Oct;
42(4):189-97.
PMID: 11033434
A cell-based, lawn format assay utilizing an in situ photocleavage method has been developed that allows the rapid examination of large bead-based compound libraries as discrete molecules. The format uses...
3.
Chen G, Way J, Armour S, Watson C, Queen K, Jayawickreme C, et al.
Mol Pharmacol
. 2000 Jan;
57(1):125-34.
PMID: 10617687
This article describes the behavior of transiently transfected human receptors into melanophores and the potential use of constitutive receptor activity to screen for new drug entities. Specifically, transient transfection of...
4.
Marotti Jr L, Jayawickreme C, Lerner M
Pigment Cell Res
. 1999 May;
12(2):89-97.
PMID: 10231196
A receptor for vasoactive-intestinal-peptide (VIP)-related peptides was functionally characterized in a cell line derived from Xenopus melanophores using a recently described microtiter-plate-based bioassay. Activation of the melanophore VIP receptor by...
5.
Jayawickreme C, Jayawickreme S, Lerner M
Methods Mol Biol
. 1998 Apr;
87:119-28.
PMID: 9523266
No abstract available.
6.
Jayawickreme C, Jayawickreme S, Lerner M
Methods Mol Biol
. 1998 Apr;
87:107-18.
PMID: 9523265
No abstract available.
7.
Jayawickreme C, Kost T
Curr Opin Biotechnol
. 1997 Nov;
8(5):629-34.
PMID: 9353232
Recent advances in the development of combinatorial automated chemical synthesis, robotic sample handling, and data collection and analysis have significantly increased the number of compounds available for screening against potential...
8.
McClintock T, Landers T, Gimelbrant A, Fuller L, Jackson B, Jayawickreme C, et al.
Brain Res Mol Brain Res
. 1997 Oct;
48(2):270-8.
PMID: 9332724
Replacing the G-protein-coupling domains of the beta 2-adrenergic receptor with homologous domains of putative olfactory receptors produced chimeric receptors which were able to stimulate pigment dispersion in Xenopus melanophores, a...
9.
Quillan J, Jayawickreme C, Lerner M
Proc Natl Acad Sci U S A
. 1995 Mar;
92(7):2894-8.
PMID: 7708744
alpha-Melanocyte-stimulating hormone (alpha-MSH) is implicated in pigmentation, central nervous system and immune system functions, growth, mitogenesis, and melanoma. Evaluation of these roles has been hindered by the lack of alpha-MSH...
10.
Jayawickreme C, Quillan J, Graminski G, Lerner M
J Biol Chem
. 1994 Nov;
269(47):29846-54.
PMID: 7961978
Structure-function relationships of alpha-melanocyte-stimulating hormone (alpha-MSH, alpha-melanotropin) were investigated and novel alpha-MSH receptor antagonists were identified. Based on the alpha-MSH-[5-13] peptide sequence, a multi-use peptide library consisting of 31,360 structurally...