C James Ingles
Overview
Explore the profile of C James Ingles including associated specialties, affiliations and a list of published articles.
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5
Citations
2031
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Recent Articles
1.
Collins S, Miller K, Maas N, Roguev A, Fillingham J, Chu C, et al.
Nature
. 2007 Feb;
446(7137):806-10.
PMID: 17314980
Defining the functional relationships between proteins is critical for understanding virtually all aspects of cell biology. Large-scale identification of protein complexes has provided one important step towards this goal; however,...
2.
Krogan N, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, et al.
Nature
. 2006 Mar;
440(7084):637-43.
PMID: 16554755
Identification of protein-protein interactions often provides insight into protein function, and many cellular processes are performed by stable protein complexes. We used tandem affinity purification to process 4,562 different tagged...
3.
Rosonina E, Ip J, Calarco J, Bakowski M, Emili A, McCracken S, et al.
Mol Cell Biol
. 2005 Jul;
25(15):6734-46.
PMID: 16024807
In a recent study, we provided evidence that strong promoter-bound transcriptional activators result in higher levels of splicing and 3'-end cleavage of nascent pre-mRNA than do weak promoter-bound activators and...
4.
Wong J, Ionescu D, Ingles C
Oncogene
. 2003 Jan;
22(1):28-33.
PMID: 12527904
Mutations in the BRCA1 and BRCA2 genes predispose women to familial, early-onset breast cancer. Both the BRCA1 and BRCA2 proteins appear to function in the homologous recombination pathway of DNA...
5.
Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD
Emili A, Shales M, McCracken S, Xie W, Tucker P, Kobayashi R, et al.
RNA
. 2002 Oct;
8(9):1102-11.
PMID: 12358429
The carboxyl-terminal domain (CTD) of the largest subunit of eukaryotic RNA polymerase II (pol II) plays an important role in promoting steps of pre-mRNA processing. To identify proteins in human...