C J Petropoulos
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Explore the profile of C J Petropoulos including associated specialties, affiliations and a list of published articles.
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40
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1556
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Recent Articles
1.
Parkin N, Hellmann N, Whitcomb J, Kiss L, Chappey C, Petropoulos C
Antimicrob Agents Chemother
. 2004 Jan;
48(2):437-43.
PMID: 14742192
Wild-type viruses from the ViroLogic phenotype-genotype database were evaluated to determine the upper confidence limit of the drug susceptibility distributions, or "biological cutoffs," for the PhenoSense HIV phenotypic drug susceptibility...
2.
Duan C, Poticha D, Stoeckli T, Petropoulos C, Whitcomb J, McHenry C, et al.
J Infect Dis
. 2001 Oct;
184(10):1336-40.
PMID: 11679926
Cross-resistance between zidovudine, stavudine, and lamivudine was studied, using purified recombinant reverse transcriptase from a zidovudine-susceptible and -resistant pair of clinical isolates of human immunodeficiency virus type 1. The zidovudine-resistant...
3.
Dunne A, Mitchell F, Coberly S, Hellmann N, Hoy J, Mijch A, et al.
AIDS
. 2001 Aug;
15(12):1471-5.
PMID: 11504978
Objective(s): To compare antiretroviral resistance susceptibility testing of patient HIV-1 strains using genotype and phenotype methods. Design: Eighteen plasma samples with viral load > 2000 HIV-1 RNA copies/ml were randomly...
4.
Price R, Paxinos E, Grant R, Drews B, Nilsson A, Hoh R, et al.
AIDS
. 2001 Jun;
15(10):1251-9.
PMID: 11426069
Objective: Structured antiretroviral treatment interruption (STI) has been advocated as a therapeutic strategy for HIV-1 infection. We report initial observations of cerebrospinal fluid (CSF) HIV-1 infection in five patients undergoing...
5.
Johnson V, Petropoulos C, Woods C, Hazelwood J, Parkin N, Hamilton C, et al.
J Infect Dis
. 2001 May;
183(11):1688-93.
PMID: 11343221
To confirm the vertical transmission of multidrug-resistant (MDR) human immunodeficiency virus type 1 (HIV-1) and to assess its impact on further evolution of drug-resistant virus in an infant, proviral DNA...
6.
Deeks S, Wrin T, Liegler T, Hoh R, Hayden M, Barbour J, et al.
N Engl J Med
. 2001 Feb;
344(7):472-80.
PMID: 11172188
Background: In many patients with human immunodeficiency virus (HIV) infection, therapy with potent antiretroviral drugs does not result in complete suppression of HIV replication. The effect of cessation of therapy...
7.
Ziermann R, Limoli K, Das K, Arnold E, Petropoulos C, Parkin N
J Virol
. 2001 Feb;
74(9):4414-9.
PMID: 10756056
Amprenavir (Agenerase, 141-W94, VX-478) is a human immunodeficiency virus type 1 (HIV-1) protease inhibitor (PRI) recently approved for the treatment of HIV-1 infection in the United States. A major cause...
8.
Parkin N, Deeks S, Wrin M, Yap J, Grant R, Lee K, et al.
AIDS
. 2001 Jan;
14(18):2877-87.
PMID: 11153669
Background: Clinical studies have demonstrated a correlation between the response to second-line antiretroviral therapy and the number of drugs in the regimen to which the virus is susceptible. These studies...
9.
Brown A, Precious H, Whitcomb J, Wong J, Quigg M, Huang W, et al.
J Virol
. 2000 Oct;
74(22):10269-73.
PMID: 11044070
Recently, significant numbers of individuals with primary human immunodeficiency virus (HIV) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs. In one study, HIV from...
10.
Martinez-Picado J, DePasquale M, Kartsonis N, Hanna G, Wong J, Finzi D, et al.
Proc Natl Acad Sci U S A
. 2000 Sep;
97(20):10948-53.
PMID: 11005867
HIV type 1 (HIV-1) drug resistance mutations were selected during antiretroviral therapy successfully suppressing plasma HIV-1 RNA to <50 copies/ml. New resistant mutant subpopulations were identified by clonal sequencing analyses...