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C G Fields

Explore the profile of C G Fields including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 328
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Recent Articles
1.
Daragan V, Ilyina E, Fields C, Fields G, Mayo K
Protein Sci . 1997 Feb; 6(2):355-63. PMID: 9041637
Structurally characterizing partially folded states is problematic given the nature of these transient species. A peptide 20mer, T38AQLIATLKNGRKISLDLQA57 (P20), which has been shown to partially fold in a relatively stable...
2.
Fields C, GRAB B, Lauer J, Fields G
Anal Biochem . 1995 Oct; 231(1):57-64. PMID: 8678321
To better study collagen-mediated cellular and enzymatic activities, a generally applicable solid-phase methodology has been developed by which aligned triple-helical peptides (designated THPs or "minicollagens") ranging from 79 to 124...
3.
Edwards W, Fields C, Anderson C, Pajeau T, Welch M, Fields G
J Med Chem . 1994 Oct; 37(22):3749-57. PMID: 7966134
Octreotide, an analogue of the hormone somatostatin, has applications as a therapeutic and imaging agent for somatostatin-positive tumors. We have developed a generally applicable, convenient stepwise solid-phase synthetic protocol for...
4.
Nagase H, Fields C, Fields G
J Biol Chem . 1994 Aug; 269(33):20952-7. PMID: 8063713
Members of the matrix metalloproteinase (MMP) family have been implicated in disease states such as arthritis, periodontal disease, and tumor cell invasion and metastasis. Stromelysin 1 (MMP-3) has a broad...
5.
Rao G, Fields C, White J, Fields G
J Biol Chem . 1994 May; 269(19):13899-903. PMID: 8188668
Platelet activation and aggregation by fibrillar collagens are based on substrate primary, secondary, tertiary, and quaternary structure. Although several peptides incorporating sequences from the triple-helical domains of types I and...
6.
Fields C, Fields G
Methods Mol Biol . 1994 Jan; 35:29-40. PMID: 7894606
No abstract available.
7.
Fields C, Lovdahl C, Miles A, Hagen V, Fields G
Biopolymers . 1993 Nov; 33(11):1695-707. PMID: 8241428
A generally applicable solid-phase methodology has been developed for the synthesis of triple-helical polypeptides incorporating native collagen sequences. Three nascent peptide chains are C-terminal linked through one N alpha-amino and...
8.
Fields C, Mickelson D, Drake S, McCarthy J, Fields G
J Biol Chem . 1993 Jul; 268(19):14153-60. PMID: 8314781
A great variety of cells, such as melanoma cells, fibroblasts, platelets, keratinocytes, and epithelial cells, adhere to and migrate on specific regions within the triple-helical domains of types I, III,...
9.
Fields C, VanDrisse V, Fields G
Pept Res . 1993 Jan; 6(1):39-47. PMID: 8439735
The efficacy of Edman degradation sequence analysis for evaluating the synthetic efficiency of peptide-resin assembly by 9-fluorenylmethoxycarbonyl (Fmoc) solid-phase methodology has been studied. Prior researchers have described the use of...
10.
Fields C, Loffet A, Kates S, Fields G
Anal Biochem . 1992 Jun; 203(2):245-51. PMID: 1416021
Ten phenylthiohydantoin (PTH) amino acids possessing allyl (Al) or allyloxycarbonyl (Aloc) side-chain-protecting groups have been characterized by high-performance liquid chromatography for use in Edman degradation sequence analysis. Optimized separation of...