C Forbes Dewey Jr
Overview
Explore the profile of C Forbes Dewey Jr including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
358
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0
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Recent Articles
1.
Grass M, McDougal A, Blazeski A, Kamm R, Garcia-Cardena G, Dewey Jr C
J Biol Chem
. 2022 Feb;
298(5):101693.
PMID: 35157851
If a coronary blood vessel is occluded and the neighboring cardiomyocytes deprived of oxygen, subsequent reperfusion of the ischemic tissue can lead to oxidative damage due to excessive generation of...
2.
A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide
Surendran A, Dewey Jr C, Low B, Tucker-Kellogg L
BMC Mol Cell Biol
. 2021 Oct;
22(Suppl 1):47.
PMID: 34635055
Background: RhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation. There are multiple forms of cross-talk between the RhoA/ROCK...
3.
McDougal A, Dewey Jr C
J Biol Chem
. 2017 May;
292(28):11760-11776.
PMID: 28487363
Heart disease remains the leading cause of death globally. Although reperfusion following myocardial ischemia can prevent death by restoring nutrient flow, ischemia/reperfusion injury can cause significant heart damage. The mechanisms...
4.
Chua H, Bhowmick S, Tucker-Kellogg L, Dewey Jr C
Bioinformatics
. 2015 Jun;
31(20):3306-14.
PMID: 26079348
Motivation: Target characterization for a biochemical network is a heuristic evaluation process that produces a characterization model that may aid in predicting the suitability of each molecule for drug targeting....
5.
Seah B, Bhowmick S, Dewey Jr C
Methods
. 2014 Jul;
69(3):247-56.
PMID: 25009128
The study of genetic interaction networks that respond to changing conditions is an emerging research problem. Recently, Bandyopadhyay et al. (2010) proposed a technique to construct a differential network (dE-MAPnetwork)...
6.
Seah B, Bhowmick S, Dewey Jr C
Bioinformatics
. 2014 May;
30(18):2619-26.
PMID: 24872427
Motivation: Given the growth of large-scale protein-protein interaction (PPI) networks obtained across multiple species and conditions, network alignment is now an important research problem. Network alignment performs comparative analysis across...
7.
Giantsos-Adams K, Koo A, Song S, Sakai J, Sankaran J, Shin J, et al.
Cell Mol Bioeng
. 2013 Jun;
6(2):160-174.
PMID: 23805169
The local hemodynamic shear stress waveforms present in an artery dictate the endothelial cell phenotype. The observed decrease of the apical glycocalyx layer on the endothelium in atheroprone regions of...
8.
Koo A, Nordsletten D, Umeton R, Yankama B, Ayyadurai S, Garcia-Cardena G, et al.
Biophys J
. 2013 May;
104(10):2295-306.
PMID: 23708369
Nitric oxide (NO) produced by vascular endothelial cells is a potent vasodilator and an antiinflammatory mediator. Regulating production of endothelial-derived NO is a complex undertaking, involving multiple signaling and genetic...
9.
Koo A, Dewey Jr C, Garcia-Cardena G
Am J Physiol Cell Physiol
. 2012 Nov;
304(2):C137-46.
PMID: 23114962
The endothelial glycocalyx, a glycosaminoglycan layer located on the apical surface of vascular endothelial cells, has been shown to be important for several endothelial functions. Previous studies have documented that...
10.
Venkatraman L, Chia S, Narmada B, White J, Bhowmick S, Dewey Jr C, et al.
Biophys J
. 2012 Sep;
103(5):1060-8.
PMID: 23009856
Transforming growth factor-β1 (TGF-β1) is a potent regulator of extracellular matrix production, wound healing, differentiation, and immune response, and is implicated in the progression of fibrotic diseases and cancer. Extracellular...